8 articles in this issue
Maria Indra Ardriyanto,Faaza Aulia Rahman,Hanaan Emilia Adi Hastuti,Edy Meiyanto,Taro Kawai,Dyaningtyas Dewi Pamungkas Putri
Interleukin 12 (IL-12) is a pro-inflammatory cytokine type 1 that has acted as a potential immunotherapy for cancer. The mechanism of IL-12 increases the activity of cytotoxic T cells and Natural Killer (NK) cells, reverse tumor-induced immunosuppression,... see more
Andhika Rachman,Cosphiadi Irawan,Aditia R.R.,Sukamto Koesnoe,Indra Wijaya
The cluster of differentiation 36 (CD36) is a multiligand receptor protein that plays a role in lipid metabolism. Its biological functions involve lipid uptake, immune recognition, inflammation, molecular adhesion, and tumor metastasis. Soluble CD36 (sCD3... see more
Julia Ramadhanti,Kharima Dwi Utami,Muhammad Hasan Bashari,Indra Wijaya
The incidence of Chronic Myeloid Leukemia (CML) in the world is approximately 1.5 cases per 100,000 individuals. The level of resistance to CML treatment, imatinib in Indonesia is relatively high compared to Europe. Culturing CML cells can be used as a mo... see more
Resti Gradia Dwiwina,Sarah Sabrina,Yuni Susanti Pratiwi,Putri Halleyana,Adrikni Rahman,Muhammad Hasan Bashari
Colorectal cancer is one of the most diagnosed cancers in the world. KRAS mutations in colon cancer are being responsible for the progressiveness and resistance of the standard therapeutic available. Marine sponge is one the sources for chemotherapy. Styl... see more
Riri Fauziyya,Winni Nur Auli,Nisa Yulianti Suprahman,Sarmoko Sarmoko,Arif Ashari,Kalista Alsadila,Lanita Agustin,Safia Fazila,Miralda Zahra,Esteria Christina Pane,Sukrasno Sukrasno
The prevalence of colorectal cancer (CRC) is ranked third among all cancer types in both men and women, highlighting the urgency for drug exploration. Zerumbone and its derivatives have gained attention for their ability to inhibit angiogenesis, invasion,... see more
Nuha Haifa Arifin,Rifki Febriansah,Melany Ayu Octavia,Ivana Kinanti Kenyori
Cancer deaths increase every year, including in Indonesia. The low selectivity of chemotherapy agents and the resistance of cancer cells against chemotherapy agents is the main cause of chemotherapy treatment failure. It causes serious side effects in suf... see more
Sarmoko Sarmoko,Afif Hariawan Pratama,Nur Amalia Choironi,Muhammad Salman Fareza
Morusin, an active constituent of the mulberry plant (Morus alba), exhibits inhibitory effects on several types of cancer cells in vitro, including breast cancer. This study aimed to identify potential target proteins of morusin, investigate the binding e... see more