30 articles in this issue
Herci´lia Guimara~es,Manuela Rodrigues,Ma´rio Mateus
The authors aim to provide a description of the beginning of neonatal transport in Portugal and remember all professionals, doctors and nurses who voluntarily dedicated themselves to this cause for more than two decades with great commitment.Neonatal tran... see more
Daniela Fanni,Margherita Fanos,Clara Gerosa,Flaviana Cau,Erika Pisu,Peter Van Eyken,Rossano Ambu
Human lungs are composed of more than 40 cell types. The lung is classified as a “conditionally renewing” tissue and is able of a quick response to cellular damage thanks to the presence of multiple stem/progenitor cells. Embryonic and fetal progenitors a... see more
Gavino Faa,Vassilios Fanos,Melania Puddu,Alessandra Reali,Angelica Dessì,Giuseppina Pichiri,Clara Gerosa,Daniela Fanni
The finding of stem/progenitor cells in the maternal milk and the discovery of their multilineage potential, associated with some evidence regarding the ability of maternal cells to cross the gastrointestinal barrier and integrate into the organs of the b... see more
Armando Faa,Elvira Podda,Vassilios Fanos
The identification of cardiac progenitor cells in mammals raises the possibility that the human heart contains a population of stem cells capable of generating cardiomyocytes and coronary vessels. Several recent studies now show that the different cell ty... see more
Daniela Fanni,Clara Gerosa,Federica Lai,Peter Van Eyken,Gavino Faa
Stem/progenitor cells in the adult liver are able to differentiate both into hepatocyte and cholangiocyte lineage. The identification and the role of human liver stem/progenitor cells has been a challenge topic in the recent scientific literature. The exi... see more
Lidia B. Giu´dici,Vivian S. Bokser,Sergio G. Golombek,Carlos C. Castrillo´n,Mo´nica Trovato,Claudia C. Ferrario
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Anirban Mandal,Puneet Kaur Sahi
Dear Editor,We read with great interest the article by Taksande et al. published in the latest issue of your journal. First, we would like to commend the authors for their endeavor. We have comments regarding the methodological issues which require furthe... see more
Amar Taksande,Mayuri Yeole
Dear Editor,We thank the authors for their interest and comments on our paper. They have raised some very valid points.
Carlo Valerio Bellieni,Monica Tei,Giuseppe Buonocore
Neonatal pain treatment requires personalization, and pain assessment should be contextualized to be effective. Here we summarize the available tools in neonatal analgesia, paying a special attention to highlight the personalization of antalgic behavior, ... see more
Yasser Elsayed,Mary Seshia,Reeni Soni,Ilan Buffo,Ronald J. Baier,Patrick J. McNamara,Shyamala Dakshinamurti
Mohammed M.J. Alqahtani
Introduction: Preterm survivors from the neonatal intensive care unit (NICU) are considered as high risk group for some neurobehavioral impairments such as cognitive disabilities, developmental delays, social/emotional limitations, attention-deficit/hyper... see more
Ariana Silva,Paulo Soares,Filipa Flor-de-Lima,Cláudia Moura,José Carlos Areias,Hercília Guimarães
Anna De Magistris,Maria Antonietta Marcialis,Melania Puddu,Angelica Dessi`,Roberta Irmesi,Elisabetta Coni,Vassilios Fanos
It is possible to distinguish two phases in the development and maturation of the intestine: intra-uterine and extra-uterine. Up until the 13th week of the embryological phase, a fetus’ development is not controlled by factors external to the alimentary c... see more
Eleonora Obinu,Giorgia Locci,Clara Gerosa,Vassilios Fanos,Laura Vinci,Gavino Faa,Rossano Ambu,Cristina Loddo,Elisabetta Coni,Marco Angiolucci,Claudia Fanni,Daniela Fanni
The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment su... see more
Maria Antonietta Marcialis,Elisabetta Coni,Maria Cristina Pintus,Alberto Ravarino,Vassilios Fanos,Carlo Coni,Gavino Faa
Metabolomics has provided new insight into the biology that drives the phenotype of stem cells. During the recent years, metabolic circuits of embryonic and neural stem cells (NSCs) have been better elucidated. Many factors contribute to stem cell determi... see more
Melania Puddu,Claudia Fanni,Cristina Loddo,Vassilios Fanos
The growing interest of research in the field of renal stem cells and kidney regeneration aims to get results that allow its clinical application, favoring the birth and development of regenerative medicine.Nephrogenesis requires differentiation into epit... see more
Nuno Medeiros,Gustavo Rocha,Tiago Henriques-Coelho,Carla Ramalho,Hercília Guimarães
The aim of this paper is to report the experience of a level III Neonatal Intensive Care Unit (NICU) in CCAM cases.
Pallavi Sachdeva,Priyanka Minocha,Anita Choudhary,Sadasivan Sitaraman,Manisha Goyal
Rubinstein-Taybi Syndrome (RSTS) is a rare multiple congenital anomaly syndrome. Only 250 cases have been described in medical literature. We hereby present a 10-month-old male child with characteristic facial features and hand and feet anomalies. The cha... see more
I´ris Santos Silva,Filipa Flôr-de-Lima,Gustavo Rocha,Inês Alves,Hercília Guimarães
Sofia O. Correia,André M. Graça,Isabel Sampaio,Carlos Moniz,Maria do Céu Machado
This study aims to assess the adequacy of temperature control during transport of patients referred for therapeutic hypothermia at our centre and to evaluate the occurrence of complications when temperature control is not adequate. Transport data of patie... see more
Giorgia Locci,Anna Paola Pinna,Angelica Dessi`,Eleonora Obinu,Clara Gerosa,Maria Antonietta Marcialis,Maria Cristina Pintus,Marco Angiolucci,Vassilios Fanos,Rossano Ambu,Gavino Faa
Early pancreas development, given its complexity, is generally considered as a paradigm for branching morphogenesis and for the development of two organs in one: the Langherans islets, programmed to secrete hormones into the bloodstream, and the exocrine ... see more
Rossano Ambu,Clara Gerosa,Giorgia Locci,Eleonora Obinu,Alberto Ravarino,Anna De Magistris,Alessandra Reali,Peter Van Eyken,Gavino Faa,Silvia Nati,Laura Vinci
In the first part of this review a brief summary of the embryology and histology of the gastrointestinal tract is provided. In the second part intestinal stem cells (ISCs) are discussed. Several signaling pathways play a crucial role in the crypt base in ... see more
Clara Gerosa,Vassilios Fanos,Melania Puddu,Giovanni Ottonello,Gavino Faa,Bernadette Pinna,Peter Van Eyken,Daniela Fanni
The renal stem cell niche represents the most important structure of the developing kidney, responsible for nephrogenesis. Recently, some Authors have reported, at ultrastructural level, a previously unknown complexity of the architecture of renal stem ce... see more
Pasqua Anna Quitadamo,Antonio Villani,Piero Paolo Cristalli,Marina Marinelli,Anita Riganti,Michele Bisceglia,Alberto Gatta
Subcutaneous fat necrosis (SCFN) of the newborn is an uncommon form of panniculitis that occurs after fetal distress and involves fatty areas during the first weeks of life. This rare disorder is generally self-limiting and undergoes complete regression. ... see more
Ana Oliveira,Paulo Soares,Filipa Flor-de-Lima,Ana Lui´sa Neves,Herci´lia Guimara~es
Marjana Jerkovic Raguž,Jerko Brzica,Sanja Rozic,Darinka Šumanovic Glamuzina,Antonija Mustapic,Marija Novakovic Bošnjak,Tomica Božic
Gavino Faa,Vassilios Fanos,Antonio Giordano
The salamander limb regenerates completely after amputation and the heart of the zebrafish returns to normal even after an extensive injury. What is it that makes all this possible? The answer is the presence of stem cells, which in these animals are quit... see more
--- Various Authors
LECT 1. NEONATAL CONGENITAL HEART DISEASE: WHAT'S NEW? • S. Costa, U. BottoneLECT 2. THE PRETERM NEWBORN INFANT WITH PATENT DUCTUS ARTERIOSUS: TO TREAT IT? HOW TO MANAGE IT? WHEN TO TREAT IT? • C. CavalliLECT 3. CONGENITAL CARDIOPATHies IN CHILDREN WITH D... see more
ABS 1. ABNORMAL FETAL GROWTH ALTERS THE METABOLIC PROFILE OF EARLY HUMAN MILK • A. Kontogeorgou, Ch. Fotakis, D.D. Briana, T. Boutsikou, A. Malamitsi-Puchner, P. ZoumpoulakisABS 2. VENTED BASE FEEDING BOTTLE IN PRETERM INFANTS WITH GERD SYMPTOMS: EFFECTS ... see more
LECT 1. LUNG RECRUITMENT STRATEGIES AND EARLY SURFACTANT IN NEONATAL INTENSIVE CARE UNIT. PRESENTATION OF A RANDOMIZED CONTROLLED TRIAL: EFFICACY OF A NEW TECHNIQUE (IN-REC-SUR-E) IN PRETERM NEONATES WITH RESPIRATORY DISTRESS SYNDROMEG. Vento,... see more