35 articles in this issue
Sam Scott, Sam Shepherd, Jay Wright, Robert Copper, Anton Wagenmakers, Matt Cocks
Objective Obesity and inactivity lead to structural and functional muscle microvascular impairments associated with development of chronic disease. This study is the first to investigate the effect of a novel home-based high-intensity interval training (H... see more
Xiaolin Yang, Yang Hu, Yanchun Li, Tao Mei, Lijing Gong
Objective To explore the association between the polymorphism of angiotensin II receptor type 1 gene(AGTR1) and elite endurance athlete performance and the mechanism of how the polymorphism works.Methods (1) Polymorphism of AGTR1 rs5182 between 122 elite ... see more
Xiaoguang Liu, Weihua Xiao, Lifang Zhen, Yongzhan Zhou, Jian Shou
Objective Skeletal muscle contusion is one of the most common muscle injury in sports medicine and traumatology. Bone marrow mesenchymal stem cells (BMSCs) transplantation is a promising strategy for muscle regeneration. However, the roles of BMSCs, espec... see more
Yuncai Fan, Qi Yan
Objective To explore the usage of heart rate and derivative index, such as quick recovery index (QRI) and training impulse (TRIMP), to monitor and evaluate load level at physical training course. With simplified load evaluation program, we can accurately ... see more
Daniil Popov, Pavel Makhnovskii, Evgeny Lysenko, Olga Vinogradova
Objective Variety of processes including circadian rhythm and systemic factors affect expression of many genes in skeletal muscle during a day. Therefore, post-exercise gene expression depends on many factors: contractile activity per seas well as circadi... see more
Katie Hesketh, Latthew Cocks, Sam Shepherd, Anton Wagenmakers, Juliette Strauss
Objective Currently 40% of the UK do not meet the physical activity guidelines with a ‘lack of time’ the most commonly cited barrier to sufficient physical activity. In laboratory based training interventions, high intensity interval training (HIT) offers... see more
Zhengtang Qi, Jie Xia, Xiangli Xue, Xingtian Li, Zhiming Cui, Xue Zhang, Lu Cao, Liu Weina, Ding Shuzhe
Objective Recent studies suggest that chronic stress exposure can ameliorate the progression of diet-induced prediabetic disease, by inhibiting an increase in weight gain, caloric intake and efficiency and insulin resistance. To determine the underlying m... see more
Xian Guo, Jianmin Cao, Yi Wang, Haitao Zhou, Jing Zhang, Yanlong Niu, Ge Hu
Objective Long-term intensive training may led to ischemia oxygen reaction and increase the ROS. Astaxanthin, as the super antioxidant, was investigated to against anti-oxidative stress. By supplementing the astaxanthin, we wanted to observe if it can med... see more
Louise Deldicque, Olouyomi Gnimassou, Geoffrey Warnier, Nicolas Benoit, Damien Naslain, Henri Nielens, Marc Francaux
Objective Hypoxia is a state of lowered oxygen tension in tissue that can be created by environmental or pathological conditions. Whatever the origin of hypoxia, different tissues will adapt acutely and/or chronically to deal with this reduction in oxygen... see more
Shan Chen, Peizhen Zhang
Objective Overweight was a global public health problem. In recent years, the number of overweight people in China had been increasing. Being overweight had a serious impact on health. 31.1% of overweight people had aggregation of risk factors for cardiov... see more
Junhao Huang, Min Hu, Weiyue Yang, Mengke Zhao
Objective Increasing evidence has shown that moderate-intensity aerobic exercise training reduces airway hyperresponsiveness (AHR) in patients with asthma. However, the mechanisms underlying exercise-induced improvements in smooth muscle contractility hav... see more
Chris Shaw, Courtney Swinton, Maria Gabriela Morales Scholz, Tasman Erftemeyer, Andrew Aldous, Robyn Murphy, Kirsten Howlett
Objective A greater capacity for fat oxidation in endurance trained athletes is linked to greater utilisation of intramuscular lipid (IMCL). IMCL breakdown occurs only in type I muscle fibres yet little is known about the fibre type specific abundance of ... see more
Katie Whytock, Siôn Parry, Mark Turner, Lewis James, Richard Fergusson, Carl Hultson, Juliette Strauss, Matt Cocks, Anton Wagenmakers, Sam Shepherd
Objective High-fat high-calorie diets can induce whole body insulin resistance (IR) whilst increasing stores of intramuscular triglyceride (IMTG) contained within lipid droplets (LD). Perilipin (PLIN) proteins assist in IMTG storage. Synaptosomal-associat... see more
Sulin Cheng, Moritz Schumann, Petri Wiklund
Objective The role of exercise in the prevention and treatment of chronic diseases is widely accepted and regular physical exercise may play an irreplaceable role beyond traditional medicine and drug treatments. However, current guidelines do not pr... see more
Ning Jiang, Zhe Wang, Jing Li, Xinghao Wang
Objective To investigate whether the liver autophagy level can be altered by pre exercise training in mice liver tumors.Methods 40 Male C57BL/6J mice aged 7 months were randomly divided into 2 groups: control group (YC) and e... see more
Tiantian Wang, Ziyi Zhang, Hai Bo, Yong Zhang
Objective To establish a skeletal muscle-specific PGC-1a overexpression mouse model via in vivo local transfection.Methods For the PGC-1a in vivo transfection study, the Male FVB/N mice were randomly divided into 2 groups: subject to g... see more
Wenping Feng, Junfen Zhang, Wenyuan Shang, Pingxue Qiu, Aiqi Yu
Objective Objective: This study was to investigate the body under high temperature (33 ?) with different relative humidity (80%, 50%, 20%) combination of environment, respectively for 20 min 60% VO2max individual strength of quiet before and after the exp... see more
Lijuan Hou, Xudong Zhao, Ke Li, Mengjiao Chen, Jiaxin Li, Decai Qiao
Objective Objective: After injection of D2DR antagonist and agonist, the autonomic activity and striatal neurons electrical activity of rats with exercise-induced fatigue were recorded to explore the role of DA receptors in the central mechanism of ... see more
Hong Gu, Qiang Tang
Objective This thesis provides a theoretical basis for improving children’s physical activity levels and promoting the healthy development of primary school children.Methods Measuring the height, shape index of children which are in 3-5 grades of primary ... see more
Piyushan Gunawardhana, Nalinda Silva
Objective Handgrip strength is a marker of upper body strength. The purpose of this study is to examine the relationship between the dominant handgrip strength and twelve selected parameters of cricket players in Sri Lanka Prison Department. The twelve se... see more
Glenn McConell, Kim Sjøberg, Frederik Ceutz, Lasse Gliemann, Michael Nyberg, Ylva Hellsten, Christian Frøsig, Bente Kiens, Jørgen Wojtaszewski, Erik Richter
Objective The relationship between skeletal muscle perfusion, interstitial glucose concentration and sarcolemmal permeability to glucose in exercise-induced increases in muscle insulin sensitivity is not well established. A single bout of exercise increas... see more
Mengxin Cai, Shaojun Du, Zhenjun Tian
Objective Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. Exercise training could improve cardiac function following MI. However, the mechanisms are still not well-known. Neuregulin 1 (NRG1)plays an important role ... see more
Guoliang Fang, Jiexiu Zhao, Li Zhang, Pengfei Li
Objective Many studies suggest that regular physical exercise can reduce the risk of Alzheimer’s disease and slow its onset and progression. However, the exact mechanism is still unclear. Clinically, Alzheimer’s disease is characterized by the presence of... see more
Qi Han, Jinde Fu, Jing Shao, Qirong Wang, Zilong Fang, Hong Gao, Lili Zhou, Muqing Yi
Objective To examine biochemistry parameters regarding exercise induced fatigue, e.g. Sweat Loss (SL), Creatine Kinase (CK), Lactate Dehydrogenase (LDH), Blood Urinary Nitrogen (BUN), etc.Methods This study examined Sweat Loss and blood biochemistry bioma... see more
Xu Yan, Shanie Landen, Macsue Jacques, Ioannis Papadimitriou, Jujiao Kuang, Andrew Garnham, Jia Li, David Bishop, Sarah Voisin, Nir Eynon
Objective Angiotensin Converting Enzyme (ACE) is expressed in human skeletal muscle. The ACE I/D polymorphism (rs4341) has been associated with athletic performance in some studies. Studies suggested that the ACE I/D gene polymorphism is associated ... see more
Ilkka Heinonen, Kari Kalliokoski, Vesa Oikonen, Christopher Mawhinney, Warren Gregson, Helen Jones, David Low, Tim Cable, Li Huo, Juhani Knuuti, Chunlei Han
Objective Skeletal muscle is unique among organs in that its blood flow, thus oxygen supply that is critical for muscular function, can change over a remarkably large range. Compared to the rest, muscle blood flow can increase over 20-fold during intense ... see more
Boris Shenkman, Natalia Vilchinskaya, Kristina Sharlo
Objective It is well known, that the reduced contractile activity of the postural soleus muscle under bedrest, immobilization or a space flight leads to decrease of slow myosin heavy chain (MyHC) expression rate and increase of the fast myosin isoforms ex... see more
Brian Carson, Robert Davies, Joseph Bass, Catherine Norton, Bijal Patel, Miryam Amigo-Benavent, Sylvia Murphy, Patrick Kiely, Patrick Kiely, Philip Jakeman
Objective The aim of this research was the development and validation of a translational model for the evaluation of exercise and nutrient stimulated muscle protein synthesis (MPS). To achieve this overall aim, three primary objectives had to be realised:... see more
Fei Qin, Jiexiu Zhao, Mingxiao Xu, Yanan Dong, Zhongwei Wang
Objective Exposure of PM2.5 has been associated with adverse respiratory and the risk of inflammation. While regular physical activity (PA) reduces the risk of many adverse health effects. This study aimed to examine the protection of pre-exercise on adve... see more
Xiaowei Ojanen, Moritz Schumann, Shenglong Le, Yuan Zhang, Tao Huang, Petri Wiklund, Sulin Cheng
Objective Lactic acidosis is typically caused by an imbalance in lactic metabolism. This may be attributed to several reasons and is usually a result of complex interactions. There may be an increased risk for lactic acidosis in type 2 diabetes mellitus (... see more
binghong gao, Yue Zhang, Huan Gao
Objective 12 female rowing athletes of Shanghai as research object of this study. 7 weeks of hypoxic experiment will be carried out on the study subjects. Monitoring of HRV and functional indexes of athletes during this period. To explore the effect of 3 ... see more
Timon Cheng-Yi Liu, Quan-Guang Zhang, Chong-Yun Wu, Luo-Dan Yang, Ling Zhu, Rui Duan
Objective In MSSE, we have divided male 2.5-month-old Sprague-Dawley rats into the following 4 groups: control (C), habitual swimming (SW), Alzheimer’s disease (AD) induction without swimming (AD), and habitual swimming and then AD inducti... see more
Robyn Murphy, Aaron C Petersen, Itamar Levinger, Michael J McKenna, Victoria L Wyckelsma
Objective Heat shock proteins (HSPs) are ubiquitously expressed proteins that help preserve cellular homeostasis. Within mammalian skeletal muscle three of the better characterised HSPs are HSP72, HSP27 and aB-crystallin. Among other roles, these three HS... see more
Yanyan Kang, Chengyi Liu
Objective To extract information that affect sport performance, the technique of urine metabolism and quantitative difference(QD)analysis were combined in search of the characteristic metabolites of the rowing athletes.Methods Morning urine were collected... see more
Stefan Wette, Heather K Smith, Graham D. Lamb, Robyn M Murphy
Objective Power resistance exercise involves high intensity (load and velocity) dynamic muscular contractions and is frequently performed by athletes to enhance performance via improved muscle function. To investigate the remodelling processes that contri... see more