SUMMARY
Objective: to build a proposal of care line for pregnant women infected with syphilis from the perspective of nurses. Methods: this is a qualitative research conducted with seven Primary Health Care nurses, through semi-structured interviews with aid of a script with sociodemographic and professional data and guiding questions. The technique of Content Analysis in the thematic modality was used for data analysis. Results: a central thematic unit and five categories were built, addressing the performance in Primary Health Care, difficulties and potentialities of care, the nursing process, interprofessionality, and the idealization of a care path. Conclusion: the results indicated the existence of a scenario of care to pregnant women infected with syphilis, but with minimally articulated actions. Nurses present difficulties that may interfere in the care provided, such as the fragile search for pregnant women and partners, and lack of involvement on the part of municipal management.