SUMMARY
Bereznyakova A. I., Cheremisina V. F., Mrozkowiak M., Zukow W. Enzymatic homeostasis in peripheral blood lymphocytes in rats with dermatitis = ?????????????? ????????? ? ?????????? ?????????????? ????? ? ???? ??? ??????????. Journal of Education, Health and Sport. 2015;5(11):203-216. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.33850http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2811%29%3A203-216https://pbn.nauka.gov.pl/works/669303Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartosc merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacja MNiSW z dnia 2 czerwca 2014 r., ze w roku 2014 nie bedzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 25.09.2015. Revised 25.10.2015. Accepted: 10.11.2015. UDC 616.37-002-036.11??? 616.37-002-036.11 Enzymatic homeostasis in peripheral blood lymphocytes in rats with dermatitis?????????????? ????????? ? ?????????? ?????????????? ????? ? ???? ??? ?????????? ?. ?. ???????????1, ?. ?. ??????????1, M. Mrozkowiak2, W. Zukow2A. I. Bereznyakova1, V. F. Cheremisina1, M. Mrozkowiak2, W. Zukow2 1???????????? ???????????????? ???????????, ?. ???????1National University of Pharmacy, Kharkiv2Uniwersytet Kazimierza Wielkiego, Bydgoszcz2Kazimierz Wielki University, Bydgoszcz ??????? ? ?????? ??????? ????????? ??????????????? ?????????? ???????-??????????????? ?????????? ?????????????? ????? ? ???? ? ??????????? ????????? ?????????. ????????, ??? ?????????? ?????????? ?????????? ????????? ?????? ????????????? ????????? ?????????, ??????? ????? ? ????????????????? ?????????? ? ??????; ??? ??????? ? ??????????? ????????? ????????????????????? Na+, K+-???-????? ? ?a2+, Mg2+-???-????? ??????????, ??????????? ???? ??? ? ??????????. ????????, ??? ??? ?????????? ????????? ?????????, ???????? ????????????? ???????, ?????????? ???????????? ????????? ? ?????????? ?? ???? ?????????? ?????? Na+ ? ?a2+, ??? ???????? ? ?????????????? ?????????? ? ????????? ?? ?????????????? ??????????. ???????? ?????: ?????????????? ?????????, ?????????, ?????????????? ?????, ???????, ???? – ??2+-???-??? ?????????????? ????????, SERCA – Ca2+-???-??? ???????????????????? ??????????. Summary We studied enzymatic disorders of homeostasis saponin-perforated peripheral blood lymphocytes in rats with dermatitis of various etiologies. It has been shown that the stimulation of lymphocyte antigens triggers a cascade of energy-dependent processes, which lead to a redistribution of macroergs in a cage; is associated with a significant decrease in ouabainsensitive Na+, K+-ATP-ase and ?a2+, Mg2+-ATP-ase activity, a decrease in the pool of ATP in lymphocytes. It is proved that the dermatitis of various etiologies, especially allergic nature violated regulatory mechanisms in lymphocytes due to overload Na+ ? ?a2+, leading to disruption of the energy deficit lymphocytes and their functional activity. Tags: enzymatic homeostasis, cells, peripheral blood, saponin, RMSA - ??2+-ATPase of plasmic membrane, SERCA - Ca2+-ATPase of sarcoplasmic reticulum. ??????? ???????????? ????????? ? ?????????? ???????????? ????? ? ????? ??? ??????????. ? ?????? ??????? ????????? ????????????? ?????????? ???????-???????????? ?????????? ???????????? ????? ? ????? ? ??????????? ?????? ?????????. ????????, ?? ?????????? ?????????? ?????????? ???????? ?????? ??????????? ???????? ????????, ??? ?????? ?? ????????????? ?????????? ? ???????; ?? ???'????? ? ??????????? ????????? ??????????????? Na+, K+-???-????? ?? ?a2+, Mg2+-???-????? ??????????, ?????????? ???? ??? ? ??????????. ????????, ?? ??? ?????????? ?????? ?????????, ???????? ?????????? ???????, ??????????? ??????????? ????????? ? ?????????? ?? ??????? ?????????????? ?????? Na+ ? ?a2+, ?? ?????????? ?? ?????????????? ?????????? ? ????????? ?? ?????????????? ??????????. ??????? ?????: ???????????? ?????????, ?????????, ??????????? ????, ???????, ???? – ?a2+-???-??? ???????????? ????????, SERCA – ?a2+-???-??? ?????????????????? ??????????.