ARTICLE
TITLE

Metabolic syndrome - diagnostics, pathophysiology and treatment

SUMMARY

AbstractMetabolic syndrome, though it is not a disease included in ICD-10, is a serious epidemiological problem as much as a challenge for medicine and prevention of developed countries. The aim of this work is to discuss, based on literature, the basics of pathophysiology, diagnostic criteria and principles of treatment of the metabolic syndrome. The diagnosis of the metabolic syndrome is based on simple criteria, which include: abdominal circumference, blood pressure and triglycerides, HDL cholesterol and glucose levels. This allows the diagnosis of the metabolic syndrome at the level of primary care. The basis for treatment of the metabolic syndrome is behavioural therapy, sometimes, at non-advanced stage of the disease, it is sufficient. Due to the significant progress in pathophysiology of the metabolic syndrome, it is possible to determine its primary causes and risk factors - obesity and insulin resistance. Both of them belong to the reversible states, which is motivation to detect and treat these conditions before irreversible complications develop.

 Articles related

Abdullah Al Hazmy,Muchsin Doewes,Noer Rachma,Agus Kristiyanto    

ObjectivesThe prevalence of obesity in childhood and adolescence is a major public health problem and has increased dramatically over the last few decades. More attention is needed because it is closely related to some non-communicable diseases and metab... see more


S. Gushcha,B. Nasibullin,W. Zukow,I. Savitskyi,V. Volyanska    

In white rats in the setting of development of metabolic syndrome inhibition of the urinary and excretory functions of the kidney, with impaired water-ion balance (the kidneys excrete slightly hyperosmotic urine in a small amount) on the background of ... see more


I. P. Dvulit    

Aim: To investigate periodontoprotective action of 2 phytopreparations: husks of grapes meal and oak extract at the metabolic syndrome.Methods: The metabolic syndrome was reproduced into rats by used high fat diet, dysbiosis and introduced cytostatic. Th... see more


V. L. Vasiuk,A. P. Levitsky,E. M. Levchenko    

Modeling of experimental metabolic syndrome in Wistar male rats was accompanied by a sharp increase in neutrophils/lymphocytes ratio and decrease in the numbers of monocytes in the blood, as well as almost 5-fold increase in the urease activity, a 3-fold... see more


T. A. Pyndus    

Introduction. Given the increasing prevalence of metabolic syndrome among the population, the search for ways to treat and prevent major dental diseases in this somatic pathology is of great importance.Purpose of the study. The purpose of this work was t... see more