Yograj Guggul (YG) is a poly-herbal formulation extensively used by Ayurvedic practitioners to treat inflammatory conditions. However there are no reports evaluating its effect on the various enzymes involved in the inflammatory pathway. Hence the presen... see more

Revista: International Journal of Phytomedicine

Open Access

5-Methoxyhydnocarpin shows selective anti-cancer effects and induces apoptosis in THP-1 human leukemia cancer cells via mitochondrial disruption, suppression of cell migration and invasion and cell cycle arrest

Xiao-Yan Xu, Hui-Rui Wang, Shu-Li Guo, Bo Li, Tao Lv

The primary objective of the current investigation was to study the anti-tumor effects of 5-methoxyhydnocarpin in THP-1 human leukemia cells along with evaluating its effects on apoptotic induction, cancer cell migration and cell cycle phase distribution... see more

Revista: Bangladesh Journal of Pharmacology

Open Access

Eriodictyol-induced anti-cancer and apoptotic effects in human hepatocellular carcinoma cells are associated with cell cycle arrest and modulation of apoptosis-related proteins

Fang Wang, Yu-Hang Wang, Jing-Jing Wang, He-Lin Xu, Chang-Miao Wang

The objective of the present study was to investigate the anti-cancer effects of eriodictyol in human hepatocellular carcinoma cells (Hep-G2) and normal liver hepatocyte cell line (AML12) along with evaluating its mode of action. Sulforhodamine B assay w... see more

Revista: Bangladesh Journal of Pharmacology

Open Access

A novel synthesis of aurones: Their in vitro anticancer activity against breast cancer cell lines and effect on cell cycle, apoptosis and mitochondrial membrane potential

Hai Chen, Xiao-Dong Qi, Ping Qiu

A novel method for the synthesis of aurones from benzofuran-3(2H)-one by condensation with aromatic aldehydes is described. The anticancer activity of the synthesized compounds was evaluated by MTT assay and among the series of 15 compounds, (Z)-2-(4-met... see more

Revista: Bangladesh Journal of Pharmacology

Open Access

Effectiveness of Debriefing towards Healthcare Professionals’ Nontechnical Skills: A Critical Review

MUHAMAD NUR FARIDUDDIN,WEE LEI HUM,LILIA HALIM,MOHD JOHAR JAAFAR

The importance of nontechnical skills among healthcare professionals is gaining widespread recognition as critical elements complementing technical skills that are used to improve patients’ safety. These skills are typically acquired through simulation t... see more

Revista: Jurnal Sains Kesihatan Malaysia

Open Access