ARTICLE
TITLE

Off the Shelf or Recalibrate? Customizing a Risk Index for Assessing Mortality

SUMMARY

Background: Public "report cards" for cardiac surgery have been freely available from a variety of sources. These risk-adjusted indices serve as a means of benchmarking outcomes performances, allowing comparisons of outcomes between surgical programs, and quantifying quality improvement programs. We examined two alternative strategies for using previously developed risk-adjusted mortality models in a community hospital: (1) using the model "off the shelf" (OTS) and (2) recalibrating the existing model (RM) to fit the institution-specific population. Methods: Six OTS models were used: Parsonnet (PA), Canadian (CA), Cleveland (CL), Northern New England (NNE), New York (NY), and New Jersey (NJ). The RM models were created by each model's independent variables and definitions and adjusting the weighting with logistic regression methods. The accuracy, the C statistic, and the precision of each model were assessed for in-hospital mortality. We compared the OTS version of each model to the RM version with methods detailed by Hanley and McNeil. Results: The RM C statistic was improved for all risk-adjusted models, most notably in the statistical improvement seen in the PA (0.053 improvement) and NJ (0.052 improvement) indices. Statistical gains in precision were also seen in the RM models for the PA, CL, and NNE indices. Conversely, one model, the CA model, was more poorly calibrated in the RM model compared with the OTS model, despite an improved C statistic (0.062). Conclusions: The RM strategy provides institution-explicit models that demonstrate a higher degree of accuracy and precision than the OTS models.

 Articles related

Ahmed ElGuindy,Ahmed Osman,Ahmed Elborae,Mohamed Nagy    

Paravalvular leaks (PVL) are seen in 5-17% of patients after surgical mitral and aortic valve replacement. This is usually well-tolerated in the majority of patients; however, up to 5% will require re-intervention due to either hemodynamically significan... see more


Atefeh Torknejad ,Sima Babaei ,Mohsen Mirmohammadsadeghi    

BACKGROUND: Coronary artery bypass graft (CABG) surgery is the most effective treatment for cardiovascular disease (CVD). Adherence to treatment after CABG surgery is very important. One of the educational models used in this regard is the BASNEF (Belief... see more


Morten Smerup, Troels F. Pedersen, Camilla Nyboe, Jonas A. Funder, Thomas D. Christensen, Sten L. Nielsen, Vibeke Hjortdal, J. Michael Hasenkam    

Background: Animal experimental testing is imperative for preclinical evaluation of prosthetic heart valves and implantation techniques. Because human and pig cardiovascular structures including mitral valves show remarkable anatomical similarity, these ... see more


Krishaporn Kradangnga, Eric Monnet    

Background: Surgical method of choice for functional mitral regurgitation (FMR) is debatable, since recurrence of FMR post-annuloplasty has been reported in a significant number of cases. Developing a pulsatile FMR heart model by left ventricular dilatat... see more


Yang Liu, Hongliang Wang, Xiudan Wang, Guohong Xie    

Background: To study the effect of miR-29b on myocardial infarction via Notch signaling pathway in rats.Methods: The rat acute myocardial infarction (AMI) models were established and were divided into AMI group, sham group and normal group (N = 10 in eac... see more