SUMMARY
The article is devoted to modern approaches to the treatment of acute rhinosinusitis taking into account the basic principles of the rational pharmacotherapy. Today acute rhinosinusitis (ARS) remains in the leading position among other diseases in outpatient practice, therefore, the choice of the optimal treatment tactics and the optimal drug in each clinical case is of particular importance. The drugs of choice for acute uncomplicated rhinosinusitis are herbal preparations. The phytopreparations have an effect on all links of the pathogenesis of the disease due to the complex action of their biologically active substances. The phytopreparation Sinupret® (Bionorica CE, Germany) is very often recommended by doctors and pharmacists for treating rhinitis, sinusitis and their complications. Priority of the choice of the drug is determined by its high efficiency and safety proven by numerous preclinical and clinical studies, the long experience of use and the presence of several dosage forms. Despite the common name each of the drugs of this brand has its own characteristics. They differ in the specificity of the dosage form, the physicochemical state of the active pharmaceutical substance, the dose of the active substances. Various Sinupret® modifications are important for the individualized rational pharmacotherapy of patients with ARS provided by both a physician and a pharmacist. When providing pharmaceutical care a pharmacist select over-the-counter medicines taking into account their effectiveness, safety, quality and economic expediency.