SUMMARY
For more than 150 years, gastric ulcer (GU) continues to be a health problem as a chronic, relapsing disease, which occupies the central place among diseases of the gastrointestinal tract due to severity of course, complications and mortality. Despite significant advances in the research of the pathogenesis of GU, the introduction of a large number of modern treatments, a large arsenal of anti-ulcer drugs, there is now an increase of this pathology both in Ukraine and worldwide. Today, pharmacotherapy of GU includes more than 500 different drugs and about 1000 of their combinations. For the treatment of GU a wide range of drugs is used, most of them are synthetic with a significant number of side effects and a number of contraindications. One of the ways of solving this problem is the use of herbal medical products (HMP). In gastroenterology, HMP can be used during the exacerbation of the disease as a means of complementary therapy in combination with basic drugs, as well as therapeutic and prophylactic agents at the initial stages of the disease, at the stage of antirecession therapy and in the period of rehabilitation. The plant world is a promising source of biologically active substances (BAS) that can be used for prophylaxis and in the complex treatment of GU taking into account that HMP contain valuable natural BAS (such phenolic compounds as flavonoids, tannins, hydroxycinnamic acids, coumarins, polysaccharides, amino and organic acids, etc.). In this regard, the lyophilized extract of fireweed herb (Chamaenerion angustifolium) is of considerable interest; it can be the source for obtaining a new drug with the anti-ulcerative activity. Therefore, it is advisable to study the anti-ulcer activity of the lyophilized extract of fireweed herb (LEFH) obtained from herb of the species under study.