SUMMARY
Postoperative pain (POP) is often a main complaint in patients after laparoscopic cholecystectomy (LCHE). Its presence and intensity often determine the duration of hospitalization and postoperative quality of life. Identification of the predictors of severe POP after LCHE will allow to reveal the patients at high risk, to form the treatment algorithm, to improve the treatment results, to decrease the risk of transformation into chronic pain. The purpose of the prospective study was to determine of intensive POP predictors in patients after LCHE. 100 patients were included to investigation, in 20 of them after LCHE the severe POP was appeared. The predictors of severe POP were female gender, young age, severe pain before the surgery, chronic pain, preoperative anxiety and/or depression. Patients who received ketamine during the surgery had lower rate of severe POP.