SUMMARY
The microflora and sensitivity antibiotics at 224 patients divided into two identical groups (on a floor, age and pathological process on foots) is researched: in 2000-2002 and in 2004-2006?. In dynamics - the role of aerobic flora has decreased, the share facultative anaerobic and gramnegation florae has increased. Resistency to antibiotics has changed. Between kinds of activators at various forms of a diabetic foots have not established precise correlation. In view of change in dynamics of kinds of activators and resistency of antibiotiks is recommended following schemes: ftorhinolons+ metronidazole; ftorhinolons + clindamicin; cefalosporins 3-4-?? generations + metronidazole; karbopenems+ metronidazole. Antibacterial therapy in such combination it is applied within 2-3 weeks with the control of dynamics of a microflora each 5-7 days with corresponding correction. After localization of inflammatory process transition on tabletics forms depending on sensitivity of microflora is possible. It is necessary to use a principle step antibacterial therapy. In connection with duration of antibacterial therapy the control of dynamics of a microflora not only over treatment of each patient, but also in connection with evolution ofpathogenic flora and her adaptation to new kinds and forms of antibacterial means is necessary.