SUMMARY
The level of genetic polymorphism found in An.barbirostris was obtained by employing the Random Amplified Polymorphic DNA (RAPD) method and then analyzing the patterns of DNA bands formed, some of which would be polymorphic and other monomorphic. Polymorphic DNA band frequency was calculated to obtain the persentages polymorphic of DNA bands occurring in An.barbirostris from all 10 villages. The result of DNA band pattern analysis managed to be amplificated from An. barbirostris was found to contain a different number of polymorphism in each village. The highest level of polymorphism was obtained in the sample from Cikondang village (88.9%),Cijulang (81.2%) and Rajadatu (77.8%) which are both HCI areas While in MCI areas, the level of polymorphism was lower for Ciampanan (63.6%) and Nagara Tengah (69.2%) Then, for LCI villages, the result for Pasirmukti (50%). Cisarua was 50%, Cineam was 44.5%, and Ancol was 50%. The regression analysis showed the relation of genetic variation in An. barbirostris in each village with the prevalence showing positive correlation Y = 0.692 X + 3.2, R = 0.58, p >0.05, in which the level of polymorphism affected the high level of malaria prevalence, either from SPR.