SUMMARY
Abstract . Laboratory biosecurity is the protection, control and accountability for valuable biological material ( VBM ) laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release. The efforts of biosecurity have capability to anticipate the potential probability of releasing biohazard agent from the laboratory, the risk assessment study in the infectious disease laboratories was an effort to know whether biosecurity measures were applied in the laboratory. The usage of modified checklist questionnaire of biosecurity for collecting data and observation was done to identify potential hazard in the infectious disease laboratories according to the conceptional framework of agent, host and environmental principal. The places of this assessment are in the five regional referral infectious disease laboratories , i.e., Universitas Islam Sumatera Utara (UISU) Medan, Universitas Indonesia (UI) - Jakarta, Balai Pengembangan Laboratorium Kesehatan (BPLK) - Bandung, Universitas Diponegoro (UNDIP) - Semarang , Universitas Hasanudin (UNHAS) - Makassar, one referral hospital , i.e., Rumah Sakit Umum Daerah (RSUD) - Tangerang and one national referral laboratory of Center for Biomedical and Pharmaceutical Research and Development, National Institute of Health Research and Development ( NIHRD), Ministry of Health (MOH), Jakarta. The risk assessment study was done in year 2008-2009. Physical security, personnel management and information security as components of biosecurity were not applied properly in the 7 infectious disease laboratories. Applying biosecurity in the infectious disease laboratories was very important and need to be done completely to anticipate their unauthorized access, loss, theft, misuse, diversion or intentional release.Keywords : biosecurity, bioterrorism , infectious disease laboratory, and valuable biological materials (VBM)