ARTICLE
TITLE

Effects of Anakinetic Stress and Galium verum Extract on the Thyroid and Ovary Morphology in Wistar Rats

SUMMARY

Abstract. Our study was focused on the analysis of the protective potential of the 1: 1 Galium verum hydro-alcoholic extract, on the  thyroid and ovarian morphological parameters, in the white Wistar rats in anakinetic conditions. The 15 days subcronic anakinetic stress induced by immobilization and darkness has determined an inhibition of the thyroid and ovarian functions observable in the histological aspects. Instead, the administration of the Galium verum vegetal extractract in a dose of 25 mg/100 g bw caused a stimulation of the thyroid and ovarian activity in rats subjected to a anakinetic stress of 3 hours/day and darkness for 15 days. The conclusion of this study is that Galium verum extract administration under stress conditions may have protective effects, beneficial to the morphopathological changes induced by stress.

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