SUMMARY
The aim of this study was to evaluate the diuretic activity of aqueous extract of Verbesina crocata at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular ?ltration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.Video Clip of Methodology:Method for diuretic activity: 1 min 37 sec Full Screen Alternate