ARTICLE
TITLE

Accuracy of Intraoperative Frozen Section in Diagnosing Malignancy of Ovarian Neoplasm

SUMMARY

Objective: To evaluate the accuracy of frozen section for ovarian neoplasmin our hospital.Method: A retrospective evaluation was conducted on medical recordsof patients with ovarian neoplasms who underwent a frozensection laparotomy between the years 2008 and 2013 at Dr. CiptoMangunkusumo Hospital. Records with incomplete data on frozensection or paraffin block report were excluded. Criteria for frozensection laparotomy in our facility was based on a malignancy score ofequal to or more than 6. Frozen section reports were compared toparaffin block report based on benign, borderline, or malignant cases.Result: From 139 patients with ovarian neoplasm, only 91 patientsfulfilled the inclusion and exclusion criteria. Frozen section examinationrevealed benign cases was 15.4%, borderline cases was 15.4%,and malignant cases was 69.2%. Based on histopathological type, clearcell cystoadenocarcinoma was the most commonly observed histotype(19.8%). The sensitivity of frozen section for benign, borderline,and malignancy cases respectively was 81.8%, 76.9%, 91.0%. Thespecificity of frozen section for benign, borderline, and malignancycase respectively was 93.8%, 94.8%, 91.6%.Conclusion: We found that the accuracy of intraoperative frozen sectionin our facility is adequate to diagnose ovarian neoplasm and canbe used to assist in determining the extent of surgical management.[Indones J Obstet Gynecol 2015; 3: 161-164]Keywords: frozen section, ovarian neoplasm, paraffin block, sensitivity,specitificity

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