ARTICLE
TITLE

Characteristics of the individual components of the guinea pigs’ humoral immune blood in the dynamics of the experimental bronchial asthma formation

SUMMARY

Reheda M. S., Kolishetska M. A. Characteristics of the individual components of the guinea pigs’ humoral immune blood in the dynamics of the experimental bronchial asthma formation = ?????????????? ??????? ??????????? ???????????? ????????? ????? ???????? ?????? ? ???????? ?????????? ????????????????? ???????????? ?????. Journal of Education, Health and Sport. 2015;5(4):151-156. ISSN 2391-8306. DOI: 10.5281/zenodo.16695http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%284%29%3A151-156https://pbn.nauka.gov.pl/works/553776http://dx.doi.org/10.5281/zenodo.16695Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartosc merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacja MNiSW z dnia 2 czerwca 2014 r., ze w roku 2014 nie bedzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 20.01.2015. Revised 27.03.2015. Accepted: 27.03.2015. UDC: 616.248-078.73-092.9Characteristics of the individual components of the guinea pigs’ humoral immune blood in the dynamics of the experimental bronchial asthma formation?????????????? ??????? ??????????? ???????????? ????????? ????? ???????? ?????? ? ???????? ?????????? ????????????????? ???????????? ????? M. S. Reheda, M. A. Kolishetska?. ?. ??????, ?. ?. ?????????? Danylo Halytskiy Lviv National Medical University?????????? ???????????? ???????? ??????????? ??. ?????? ?????????? AbstractIt was found rapid growth of immunoglobulin A in early period of the disease in comparison with control values, indicating apparently his particular activation and stimulation of humoral immunity in general. In the late period (26th and 33rd day) formation asthma revealed the increasing of this index, but top down direction respectively 100,0% and 45,5% opposite the first group of guinea pigs (p=0,05).As for the content of other types of antibodies, the highest level of content immunoglobulins M and G in the blood was in the fourth group of guinea pigs with asthma (26th day), indicating a direct dependence of antigenic impact on the economic performance and the body's ability to respond adequately protective response to the damaging effect factor. However, in the latest period of experimental models of disease are seeing a slight decline all parameters of humoral immunity.Evaluating the results of the research it can be concluded that stimulation of humoral immunity and the inclusion of protective mechanisms in the process, which aims are the destruction of antigens and removing them from the body of animals with experimental asthma.Key words: bronchial asthma, immune system, immunoglobulins A, M, G.  ???????? ?????? ??????????? ??????? ????????? ????? ?????????????? ? ? ???????? ??????? ????????????????? ?????? ??????? ? ?????????? ? ??????????? ??????????? ???????, ?? ???????? ???????? ??? ???? ????????? ???????, ?? ?????????? ???????????? ????????? ? ??????.  ? ????? ????? ????? (?? 26 ? 33-? ????) ?????????? ???????????? ????? ???????? ????? ?????????? ????? ?????????, ??? ?????????? ???????? ?????????? ??  100,0% ?? 45,5% ??????? ? ????? ???????? ?????? (?=0,05).???? ?????? ????? ????? ???????????????, ?? ???????? ??????? ?????? ??????????????? ? ?? G ? ????? ??? ? ????????? ????? ???????? ?????? ? ?? (?? 26-? ????), ?? ???????? ??? ????? ?????????? ???? ??????????? ?????? ?? ?????? ??? ?????????? ?? ????????? ????????? ????????? ??????????? ???????? ???????? ?? ??? ????????????? ???????. ?????, ? ??????????? ?????? ????????????????? ?????? ??????? ????????????? ????????? ???? ???? ????????????? ?????????? ??????????? ????? ?????????.???????? ?????????? ???????????, ????? ??????? ???????? ??? ?????????? ??????????? ????? ????????? ?? ??? ????????? ???????? ?????????? ? ??????, ???? ??????????? ?? ?????????? ????????? ?? ????????? ?? ? ????????? ?????? ? ????????????????? ???????????? ??????.??????? ?????: ??????????? ?????, ?????? ???????, ?????????????? ?, ?, G.               ???????? ?????? ?????????? ????????????? ???? ?????? ??????????????? ? ? ?????? ??????? ????????????????? ?????? ??????? ? ????????? ? ???????????? ??????????? ???????, ??? ??????????????? ???????? ? ??? ????????? ? ?????????, ? ?????????? ???????????? ?????????? ? ?????.  ? ????? ??????? ????? (?? 26 ? 33-?? ?????) ???????????? ???????????? ????? ?????????? ????? ????????? ????? ??????????, ?? ????????? ??????????? ?????????????? ??  100,0% ? 45,5% ???????? ? ?????? ??????? ?????? (?=0,05).???????????? ??????????? ?????? ????? ????????????????, ?? ????????? ??????? ??????????? ???????????????? ? ? G ? ????? ???? ? ????????? ?????? ??????? ?????? ?? ?? (?? 26-?? ?????), ??? ??????? ? ?????? ??????????? ??????? ??????????? ??????? ?? ??????? ???? ??????????? ? ??????????? ????????? ????????? ???????? ???????? ???????? ?? ???????? ??????????? ???????. ??????, ? ????? ??????? ?????? ????????????????? ?????? ??????? ????????? ?????????????? ???? ???? ??????????? ??????????? ???????????? ????? ??????????.???????? ?????????? ????????????, ????? ??????? ????? ? ?????????? ???????????? ????? ?????????? ? ? ????????? ???????? ?????????? ? ???????, ??????? ????????? ?? ?????????? ????????? ? ???????? ?? ?? ????????? ???????? ? ????????????????? ???????????? ??????.???????? ?????: ???????????? ?????, ???????? ???????, ??????????????? A, M, G.

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