SUMMARY
Bereznyakova A. I., Cheremisina V. F., Zhemela O. D., Zukow W. Changes in energy metabolism in rats during allergic dermatitis = ????????? ??????????????? ??????????? ? ???? ??? ????????????? ?????????. Journal of Education, Health and Sport. 2016;6(1):251-261. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.45355http://ojs.ukw.edu.pl/index.php/johs/article/view/3362https://pbn.nauka.gov.pl/works/710502 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 01.01.2016. Revised 12.01.2016. Accepted: 31.01.2016. UDC 616.37-002-036.11??? 616.37-002-036.11 Changes in energy metabolism in rats during allergic dermatitis ????????? ??????????????? ??????????? ? ???? ??? ????????????? ????????? A. I. Bereznyakova, V. F. Cheremisina, O. D. Zhemela, W. Zukow?. ?. ???????????, ?. ?. ??????????, ?. ?. ??????, ?. ????? ???????????? ???????????????? ???????????, ?. ???????, ???????National University of Pharmacy, Kharkov, UkraineUniwersytet Kazimierza Wielkiego, Bydgoszcz, PolskaKazimierz Wielki University, Bydgoszcz, Poland Abstract A study is a close relationship between the functional activity of lymphocytes and their energy metabolism in allergic dermatitis. It has been shown that acute allergic dermatitis is a disease, causing sharp changes in the energy metabolism of the skin. Established a unidirectional change in the content of adenine nucleotides in blood lymphocytes and skin homogenates in rats with allergic dermatitis. However, the concentration macroergs blood lymphocytes is significantly higher than in the homogenate of the skin. Application of 0.5% dimecine ointment pathogenetically justified. It improves energy metabolism in rats of skin with atopic dermatitis, and it is expedient to recommend to the clinical trials. Keywords: atopic dermatitis, energy metabolism, 0.5% dimecine ointment, adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP). ???????? ?????? ??????? ?????? ??????????? ????? ?????????????? ??????????? ?????????? ? ?? ?????????????? ??????? ??? ????????????? ?????????. ????????, ??? ?????? ????????????? ????????, ??? ???????????, ???????? ?????? ?????? ? ?????????????? ?????? ????. ??????????? ???????????????? ????????? ?????????? ?????????? ??????????? ? ?????????? ????? ? ?????????? ???? ? ???? ? ????????????? ??????????. ??????, ???????????? ?????????? ? ?????????? ????? ??????????? ????, ?????? ? ?????????? ????. ?????????? 0,5 % ??????????? ???? ??????????????? ??????????. ??? ???????? ?????????? ??????????????? ?????? ???? ? ???? ? ????????????? ?????????? ? ?? ????????????? ????????????? ? ??????????? ??????????. ???????? ?????: ????????????? ????????, ?????????????? ??????????, 0,5 % ??????????? ????, ????????????????? (???), ???????????????? (???), ?????????????????? (???). ???????????? ????????????? ??????????? ? ????? ??? ??????????? ?????????. ? ?????? ??????? ?????? ????????’???? ??? ?????????????? ?????????? ?????????? ?? ?? ???????????? ???????. ????????, ?? ??????? ?????????? ????????, ?? ????????????, ???????? ????? ???????? ? ????????????? ?????? ?????. ??????????? ?????????????? ????? ?????? ?????????? ??????????? ? ?????????? ????? ?? ?????????? ????? ? ????? ? ?????????? ??????????. ?????, ???????????? ?????????? ? ?????????? ????? ?????? ????, ??? ? ?????????? ?????. ???????????? 0,5% ??????????? ???? ????????????? ????????????. ???? ???????? ????????? ????????????? ?????? ????? ? ????? ? ?????????? ?????????? ? ?? ???????? ????????????? ?? ????????? ???????????. ??????? ?????: ?????????? ????????, ???????????? ??????????, 0,5 % ?????????? ????, ????????????????? (???), ???????????????? (???), ?????????????????? (???).