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Shiavax J. Rao, Andrew J. Boileau    

Alzheimer’s disease is a neurodegenerative condition associated with neurofibrillary tangles and cortical deposition of amyloid plaques. Clinical presentation of the disease involves manifestations such as memory loss, cognitive decline and dementia with... see more


Arthur Joseph, Jacob Core, Daniel Solano, Marquand Patton, Shaun Smart    

Background: Creutzfeldt-Jakob disease (CJD) is a prion disease characterized by misfolded proteins that lead to neurodegeneration and inevitable death. Classic sporadic CJD presents primarily with cognitive symptoms and ataxia without visual impairment a... see more


Oleksii Khaniukov, Valerii Chornyi, Ihor Yevstihnieiev, Ihor Hutnik, Oleksandra Smolianova, Nataliia Romuz, Kateryna Esterkina, Kateryna Pervieieva    

Background. Lesch-Nyhan syndrome is inherent X-linked recessive genetic disorder with decreased activity of hypoxanthine-guanine phosphoribosyltransferase (HGPRT). The disease is characterized by presence of the classical triad: hyperuricemia, neurologic... see more


Najma Shaheen, Mir Rooh Jan, Saghir Khan, Shazia Riaz    

Background: Long-term survivors of childhood malignancies are at increased risk of experiencing treatment-related morbidities. Survival into late adulthood in these children provides ample time for the acquisition of long-term sequelae. This study aimed ... see more


Elisabetta Cristiano, Vincenzo Marcelli, Antonio Giannone, Stefania De Luca, Flavia Oliva, Roberto Varriale, Giovanni Motta, Fiorella Paladino, Margherita Benincasa, Marco Perrella, Filippo Ricciardiello    

The Benign Paroxysmal Positional Vertigo (BPPV) represents the first cause of peripheral vertigo in populations and it is determined by a displacement of otoconial fragments within the semicircular canals. Following the patient’s head movements, these fr... see more