AKTIVITAS ANTIHIPERGLIKEMIK DARI EKSTRAK ETANOL DAN n-HEKSANA DAUN KEMBANG BULAN [Tithonia diversifolia A.Gray] PADA TIKUS PUTIH JANTAN

  • Ary Rizki Darmawi Jurusan Kimia FMIPA UNMUL
  • Chairul Saleh Jurusan Kimia FMIPA UNMUL
  • Rudi Kartika Jurusan Kimia FMIPA UNMUL

Abstract

Phytochemical test and antihyperglicemic activity from ethanol extract dan n-hexane extract from kembang bulan (Tithonia diversifolia A.Gray) leaf has been carried out. Based on the test result of phytochemistry of secondary metabolites compounds from kembang bulan (Tithonia diversifolia A.Gray) leaf showed that ethanol extract fraction containing flavonoid, fenolik, alkaloid and saponin. Whereas at n-hexane extract fraction containing alkaloid, saponin and steroid. Antihyperglicemic activity test using the method of glucose tolerance where a white male rats got induced by sucrose. Measurement of blood sugar levels using glucometer and glucose test strip. From this test shows that the most active fractions to reduce blood sugar levels was ethanol extract with a dose of 77 mg/kg BB with percentage of blood sugar levels reduction in the amount of 54.15 % it was close with reduction percentage from acarbose as positive control in the amount of 55.57 %.

Keyword
kembang bulan (Tithonia diversifolia A.Gray) leaf, phytochemistry test, antihyperglicemic activity, glucose tolerance, glucometer and glucose test strip

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Published
2015-09-22
How to Cite
DARMAWI, Ary Rizki; SALEH, Chairul; KARTIKA, Rudi. AKTIVITAS ANTIHIPERGLIKEMIK DARI EKSTRAK ETANOL DAN n-HEKSANA DAUN KEMBANG BULAN [Tithonia diversifolia A.Gray] PADA TIKUS PUTIH JANTAN. JURNAL KIMIA MULAWARMAN, [S.l.], v. 12, n. 2, p. 59-63, sep. 2015. ISSN 2476-9258. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/2>. Date accessed: 19 apr. 2024.
Citation Formats
Issue
Vol 12 No 2 (2015)
Section
Artikel

Keywords

kembang bulan (Tithonia diversifolia A.Gray) leaf, phytochemistry test, antihyperglicemic activity, glucose tolerance, glucometer and glucose test strip.

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