Methodology of creating an encapsulated dosage form with bee products. Report II
DOI:
https://doi.org/10.24959/nphj.14.1971Keywords:
bee products, granules, capsules, antiulcer effectAbstract
On the basis of experimental studies the authors have demonstrated that a topical issue of the pharmaceutical science today is development of the rational therapeutic dosage forms based on standardized biologically active substances of bee products that have specific chemical and pharmacological properties for new domestic, natural, highly effective drugs for prevention and treatment of ulcer diseases of the human gastroduodenal area. The pharmaceutical market of drugs with the antiulcer activity of different dosage forms has been analyzed. It has been found that dosage forms produced in a small range are economically and socially efficient for further development of a completely new drug based on bee products. Today science has proven that encapsulated dosage forms are promising. This dosage form is a cost effective, and allows to encapsulate various drugs from substances in the solid state to liquid and pasty ingredients. Research in recent years has confirmed that the choice of a rational dosage form of drugs in combination with excipients provide the optimal pharmacological effect of drugs under development, which production is possible both in industrial and pharmacy conditions.
References
Балткайс Я.Я., Фатеев В.А. Взаимодействие лекарственных веществ. – М.: Медицина, 1991. – С. 301.
Богдан Н.С., Тихонов О.І. // Вісник фармації. – 2014. – №1 (77). – С. 7-11.
Измалкова Н.А. Чудодействие пчелы. – Воронеж: Центр.-Чернозем. книжное изд-во, 1991. – 80 с.
Кожура І.М., Мусялківська А.О., Давидова Г.І. // Пасіка. – 1996. – №12. – С. 13-15.
Лудянський Є. // Пчеловодство. – 1991. – №10. – С. 48.
Пчелы, мед и здоровье человека. – М.: Калита, 1994. – 223 с.
Романова Е.Б. // Хим.-фарм. журн. – 1990. – Т. 24, №8. – С. 51-52.
Технология лекарственных форм / Под ред. Т.С.Кондратьевой. – М.: Медицина, 1991. – Т. 1. – С. 251-277.
Тихонов А.И., Будникова Т.Н., Меркурьева Г.Ю. // В сб. «Апитерапия и пчеловодство». – Гадяч, 1991. – С. 167-174.
Тихонов А.И., Скрыпник С.А., Ярных Т.Г., Вишневская Л.И. // Проблемы фармации, подготовки и использования провизорских кадров: Матер. респ. науч. конф. по фармации и фармакол. – Пятигорск, 1993. – С. 123-124.
Тихонов А.И., Ярных Т.Г., Будникова Т.Н. и др. // Фарм. журн. – 1991. – №3. – С. 55-58.
Тришкова Л.А., Корбут О.В., Крамарев С.А. и др. // Апитерапия и пчеловодство. – 1991. – Вып. 2. – С. 104-110.
Шуб Т.А. Антимикробная активность прополиса: вопросы стандартизации контроля качества. – Автореф. дисс. … канд. биол. наук. – М., 1982. – 20 с.
Ясницкий Ф.Ю. Современные тенденции создания и применения вспомогательных веществ лекарственных препаратов // Состояние перспективы создания новых лекарственных средств и фитохимия препаратов: Тез. докл. Всесоюзн. науч.-техн. конф. – Х., 1990. – С. 65.
Lisa Milena, Ueieertova Irena, Balloun Jan // Folia Pharm. Univ. Carolinue. – 1989. – №13. – P. 29-44.
Seifert M., Haslinger E. // Liebigs Ann. Chem. – 1998. – №11. – C. 1123-1126.
Siluta B. // J. Cron. Farm. – 1985. – Vol. 31. – S. 237-248.
A.C. 248590 ЧССР, МКИ4 А 61 К 35 / 64 Sposob pripvavy praskovaho propolisu / Lamanova Jarmila, Kovar Jozef, Skubia Frantisek. – №5054-85. Заявл.: 05.07.85. Oпубл.: 01.01.89.
Tichonov A.I., Jarnych T.G., Czernych W.P. et al. Teoria i praktyka wytwarazania leczniczych preparatow propolisowych. – M.: Apipol Farma, 2011. – S. 274.
Tichonow A.I., Sodzawiczny K., Tichonowa S.A. et al. Pylek Kwiatowy obnoze pszczele w farmacji I medycynie. – M.: Apipol Farma, 2008. – S. 273.
Tichonow A.I., Bodnarchuk L.I., Tichonowa S.A. et al. Jad pszczeli w farmacji I medycynie. – M.: Apipol Farma, 2011. – S. 240.
The United States Pharmacopeia XXI. The National Formulary XVI. – 1985. – 1683 p.
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