13 articles in this issue
Bharathi Tumkur Ramasetty, Shrisha Naik Bajpe, Sampath Kumara Kigga Kadappa, Ramesh Kumar Saini, Shashibhushan Nittur Basavaraju, Kini Kukkundoor Ramachandra, Prakash Harishchandra Sripathy
Background: Memecylon species are commonly used in Indian ethnomedical practices. The accurate identification is vital to enhance the drug's efficacy and biosafety. In the present study, PCR based techniques like RAPD, ISSR and DNA barcoding regions, such... see more
Haiyu Luo, Dan Xu, Rushan Xie, Xuping Zhang, Jian Wang, Xuejiao Dong, Daowan Lai, Ligang Zhou, Yang Liu
Background: Hyalodendriella sp. Ponipodef12, an endophytic fungus from a poplar hybrid, was a high producer of botrallin and TMC-264 with various bioactivities. In this study, the influences of eight metal ions (i.e., Mn2+, Na+, Mg2+, Zn2+, Cu2+, Fe2+, Fe... see more
Italo Thiago Silveira Rocha Matos, Edson Júnior do Carmo, Enedina Nogueira Nogueira de Assunção, Richardson Alves de Almeida, Verena Makarem Soares, Spartaco Astolfi Filho
Background: Xylitol is a five carbons polyol with promising medical applications. It can be obtained from chemical D-xylose reduction or by microbial fermentation of Sugarcane Bagasse Hemicellulosic Hydrolysate. For this last process, some microbial inhib... see more
Long Pan, Ya-kun Fang, Pei Zhou, Kui-qi Jin, Gang Wang, Yu-peng Liu
Background: The effect of diverse oxygen transfer coefficient on the L-erythrulose production from meso-erythritol by a newly isolated strain, Gluconobacter kondonii CGMCC8391 was investigated. In order to elucidate the effects of volumetric mass transfer... see more
Yu Zhang, Zhen-Hua Li, Wei Zheng, Zhen-Xing Tang, Zhi-Liang Zhang, Lu-E Shi
Background: To identify the critical amino acid residues that contribute to the high enzyme activity and good thermostability of Yersinia enterocolitica subsp. palearctica (Y. NSN), 15 mutants of Y. NSN were obtained by site-directed mutagenesis in this s... see more
Tobias Oppermann, Stefan Schwarz, Nadine Busse, Peter Czermak
Background: Mannheimia haemolytica is the primary bacterial pathogen in causing bovine respiratory disease with tremendous annual losses in the cattle industry. The leukotoxin from M. haemolytica is the predominant virulence factor. Several leukotoxin act... see more
Akram Amin Jafari, Mehran Miroliaei, Violina T Angelova, Rahman Emamzadeh, Mirjana M Djukic, Ana Djuric, Luciano Saso
Background: Synthesized aminocoumarins are heterocyclic compounds possessing potential for the treatment of insulin-dependent diabetes mellitus with unexplored anti-glycative action. Results: In this study 4-aminocoumarin derivatives (4-ACDs) were evaluat... see more
Jianhua Chen, Cuihua Wang, Huan Gao, Binlun Yan
Background: Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) with a weak estrogen-like activity in fish that is found ubiquitously in aquatic environments. However, there has been little study about BPA on the endocrine disrupting effects of cr... see more
Ling Lin, Xiaozhou Liu, Yating Zhou, Linyan Guan, Jiajia He, Weiqian Huang
Background: Endoglucanase, one of three type cellulases, can randomly cleave internal ß-1,4-linkages in cellulose polymers. Thus, it could be applied in agricultural and industrial processes. Results: A novel endoglucanase gene (JqCel5A) was cloned from J... see more
Karina Mendoza-Macedo, Alexis J. Romero-Díaz, Mariana P. Miranda-Hernández, Víctor R. Campos-García, Nancy D. Ramírez-Ibañez, L. Carmina Juárez-Bayardo, Karen Moreno-Duran, Miriam S. Cedillo-Robles, Nestor O. Pérez, Helgi Jung-Cook, Luis F. Flores-Ortiz, Emilio Medina-Rivero
Background: Developing countries have an estimate of ten times more approved biosimilars than developed countries. This disparity demands the need of an objective regulation that incorporates health policies according to the technological and economical c... see more
Rehab El-Gamal, Efstratios Nikolaivits, Georgios I. Zervakis, Gomaa Abdel-Maksoud, Evangelos Topakas, Paul Christakopoulos
Background: Many buildings in Egypt e.g. museums, mosques and churches, do not possess controlled environments for minimizing the risks of damage of wooden artifacts due to the growth of fungi. Fungal damage usually appears as change in wood color, appear... see more
Xi Bai, Xianjun Yuan, Aiyou Wen, Junfeng Li, Yunfeng Bai, Tao Shao
Background: Cold-active endo-1, 4-ß-glucanase (EglC) can decrease energy costs and prevent product denaturation in biotechnological processes. However, the nature EglC from C. farmeri A1 showed very low activity (800 U/L). In an attempt to increase its ex... see more
Xian Zhang, Dan Wu, Taowei Yang, Meijuan Xu, Zhiming Rao
Background: 3-Ketosteroid-?1 -dehydrogenase (KSDD), a flavoprotein enzyme, catalyzes the bioconversion of 4-androstene-3,17-dione (AD) to androst-1,4-diene-3,17-dione (ADD). To date, there has been no report about characterization of KSDD from Mycobacteri... see more