14 articles in this issue
Hang Qi, Xiaolin Ji, Shan Liu, Dingding Feng, Xiufang Dong, Baoyu He, Janaswamy Srinivas, Chenxu Yu
Background: Sea cucumber is a seafood of high nutritional value. During its processing, sea cucumber processing liquor is routinely produced, which is usually discarded as waste. The chemical composition of this processing liquor is similar to sea cucumbe... see more
Jiayi Wang, Lei Lu, Fujuan Feng
Background: Laccases are copper-containing enzymes which have been used as green biocatalysts for many industrial processes. Although bacterial laccases have high stabilities which facilitate their application under harsh conditions, their activities and ... see more
Chongsen Zang, Zixuan Liu, Kunmeng Yang, Rui Li, Xinxin Wang, Jizhou Zhang, Yechen Xiao
Background: Gain-of-function of fibroblast growth factor receptor 3 (FGFR3) is involved in the pathogenesis of many tumors. More and more studies have focused on the potential usage of therapeutic single-chain Fv (ScFv) antibodies against FGFR3. RNA inter... see more
David Tapia, Yoanna Eissler, Juan Carlos Espinoza, Juan Kuznar
Background: Infectious Pancreatic Necrosis Virus (IPNV) is the etiological agent of a highly contagious disease that affects salmonids. In Chile, the second worldwide salmon producer, IPNV causes great economic loss and is one of the most frequently detec... see more
Felipe Vasquez-Ponce, Sebastián Higuera-Llantén, María Soledad Pavlov, Ramón Ramírez-Orellana, Sergio H. Marshall, Jorge Olivares-Pacheco
Background: In recent years, Antarctica has become a key source of biotechnological resources. Native microorganisms have developed a wide range of survival strategies to adapt to the harsh Antarctic environment, including the formation of biofilms. Algin... see more
Xichun Zhang, Junmin Du, Yu Wang, Shuming Chen, Yingli Wang
Background: It has been a very common practice to use probiotics or their metabolites as alternative antimicrobial strategies for the treatment and prevention of infections as rampant and indiscriminate use of antibiotics causes the development of antibio... see more
Ronghuo Qin, Chuanqing Zhong, Gongli Zong, Jiafang Fu, Xiuhua Pang, Guangxiang Cao
Background: Streptomyces clavuligerus was the producer of clavulanic acid, claR, a pathway-specific transcriptional regulator in S. clavuligerus, positively regulates clavulanic acid biosynthesis. In this study, the promoter-less kanamycin resistance gene... see more
Segundo Maita, Carlos Sotomayor
Background: The yield of almonds [Prunus dulcis (Mill.) D.A. Webb] could be low due to climatic problems and any factor improving kernel size and weight, such as the use of plant bioregulators (PBRs), should be beneficial. Results: Three plant bioregulato... see more
Zilvinas Dapkunas, Aurimas Baranauskas, Gitana Mickiene, Milda Pleckaityte, Gintautas Zvirblis
Background: Gardnerella vaginalis is a bacterial vaginosis (BV)-associated vaginal bacterium that produces the toxin vaginolysin (VLY). VLY is a pore-forming toxin that is suggested to be the main virulence factor of G. vaginalis. The high recurrence rate... see more
Kuan Yan, Qin Wei, Ruizhang Feng, Wanhai Zhou, Fang Chen
Background: Cinnamomum longepaniculatum is an important commercial crop and the main source of volatile terpenoids. The biosynthesis of key bioactive metabolites of C. longepaniculatum is not well understood because of the lack of available genomic and tr... see more
Meijing He, Shunli Cui, Xinlei Yang, Guojun Mu, Huanying Chen, Lifeng Liu
Background: Because of its strong specificity and high accuracy, real-time quantitative PCR (RT-qPCR) has been a widely used method to study the expression of genes responsive to stress. It is crucial to have a suitable set of reference genes to normalize... see more
Jiajia Li, Qiong Xiao, Yufeng Huang, Hui Ni, Changzheng Wu, Anfeng Xiao
Background: Inferior Tieguanyin oolong tea leaves were treated with tannase. The content and bioactivity of catechins in extracts from the treated tea leaves were investigated to assess the improvement in the quality of inferior Tieguanyin oolong tea. Res... see more
Mariana Calin, Diana Constantinescu-Aruxandei, Elvira Alexandrescu, Iuliana Raut, Mihaela Badea Doni, Melania-Liliana Arsene, Florin Oancea, Luiza Jecu, Veronica Lazar
Background: The hydrolysis of keratin wastes by microorganisms is considered a biotechnological alternative for recycling and valorization through keratinolytic microorganisms. Despite their resistant structure, keratin wastes can be efficiently degraded ... see more
Qingheng Wang, Chuangye Yang, Ruijuan Hao, Zhe Zheng, Yu Jiao, Xiaodong Du, Yuewen Deng, Ronglian Huang
Background: C4ST-1 catalyzes the transfer of sulfate groups in the sulfonation of chondroitin during chondroitin sulfate synthesis. Chondroitin sulfate consists of numerous copies of negatively charged sulfonic acid groups that participate in the nucleati... see more