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Number 2 Year 2014

16 articles in this issue 

N. S. Bogdan,O. I. Tikhonov

On the basis of experimental studies the authors have demonstrated that a topical issue of the pharmaceutical science today is development of the rational therapeutic dosage forms based on standardized biologically active substances of bee products that h... see more

Pags. 4 - 9  

S. M. Gureeva

The place and role of the biopharmaceutical classification system have been substantiated in the article, the essence and content of biowaiver have been revealed, as well as their use in pharmaceutical development of bioequivalent solid dosage forms has b... see more

Pags. 10 - 14  

I. O. Yarema,M. I. Feodorovska

Androgenetic Alopecia (AA) treatment nowadays is still a difficult task of trichology and cosmetology as the range of medicines affecting the disease pathogenetic link and being suitable and safe to use is limited. Bearing all that in mind an increased at... see more

Pags. 15 - 19  

V. V. Shmatenko

During development of a semisolid medicinal product for the treatment of pyoinflammatory processes a special attention is paid to selection of an ointment base. The modern manufacturing of soft dosage forms for treating pyoinflammatory processes gives adv... see more

Pags. 20 - 24  

O. M. Sviechnikova,S. V. Kolesnyk,O. V. Kolesnyk

The constants of ionization pKBH + of substituted 6,9-dichloracridines have been determined in the mixed ethanol – water solvent (50 mole percent of ethanol) at the temperature of 25°C by the method of potentiometric titration. It has been shown that thes... see more

Pags. 25 - 28  

S. G. Isaev,H. O. Yeryomina,T. V. Zhukova,T. M. Kryuchkova,G. P. Zhegunova

Analysis of scientific and patent literature shows the promising results of searching biologically active compounds among derivatives of aromatic aminoacids. For many years at the Medical Chemistry department of the National University of Pharmacy the res... see more

Pags. 29 - 33  

T. O. Tsapko

To search biologically active substances among quinolone-2 sulfonyl derivatives the method for obtaining of the convenient intermediate, namely 6-allylsulfonyl-4-methyl-1,2-dihydroquinoline-2-one, has been developed. The synthesis has been carried out by ... see more

Pags. 34 - 37  

O. O. Altukhov

Analysis of scientific and patent literature testifies that search of biologically active compounds among derivatives of 2-oxoindoline is prospective. They include well-known amino acids (tryptophane), neurohormone serotonine, a number of natural alkaloid... see more

Pags. 38 - 42  

O. S. Shpychak,O. I. Tikhonov

As high-performance liquid chromatography is the most optimal method for qualitative and quantitative analysis of multicomponent medicines, including phytomedicines, – owing to the possibility to identify and quantify the substances of different volatilit... see more

Pags. 43 - 47  

M. Ye. Blazheyevskiy,O. O. Mozgova

The electrochemical behaviour of potassium hydrogenperoxomonosulfate (KHSO5) in the presence of sodium dodecylbenzenesulfonate (SDBS) has been studied using cathodic voltammetry at the carbositall electrode as indicating in the potential range of +1.0…–1.... see more

Pags. 48 - 52  

L. Yu. Klimenko,S. M. Trut,S. M. Poluyan

With the purpose of improvement of carrying out the quantitative determinations in forensic and toxicological analysis the possibility of application of the method of standard for UV-spectrophotometric determination of analytes in biological fluids has be... see more

Pags. 53 - 58  

Yana S. Kolisnyk,Alla M. Kovaleva,Olga V. Goryacha

The article presents the data of the pharmacognostic study of the aerial part of black horehound (Ballota nigra L.). The aim of the work is to determine the qualitative composition and the quantitative content of the volatile components from vegetative an... see more

Pags. 59 - 62  

L. O. Bobritskaya,M. A. Arakelyan,N. V. Popova

Literary sources indicate that among hyperendemic diseases the problems of the biliary system takeone of the leading places and are widely represented in all age groups. According to the Centre for Health Statistics of the Ministry of Public Health of Ukr... see more

Pags. 63 - 67  

M. M. Kobets,Yu. M. Kobets

The analysis of the drug assortment for treating nicotine dependence presented at the Ukrainian pharmaceutical market has been carried out according to the ATC-classification and countriesproducers with the purpose of providing the population with effecti... see more

Pags. 68 - 72  

M. V. Zarichkova

Current economic models of social protection in the EU and mechanisms of their coordination have been analysed in the article. Priorities of the social protection system development in the EU member states, including social measures, which promote innovat... see more

Pags. 73 - 77  

M. V. Rybalkin

Fungi of Candida genus are the most widespread causative agent of fungal infections. Candida causes a wide range of infections: from insignificant diseases of the skin and mucous membranes to invasion processes that can practically destroys all organs. De... see more

Pags. 78 - 81