16 articles in this issue
M. I. Romanenko,D. G. Ivanchenko,M. V. Nazarenko,M. V. Diachkov,O. M. Kamyshnyi,N. M. Polishchuk
The work is devoted to development of the method for the synthesis of 8-amino-7-(2-hydroxy-2-phenylethyl)-3-methylxanthines and the study of their physicochemical and biological properties. Purine derivatives have long been used as antiviral agents (acycl... see more
T. A. Suleymanov,E. Z. Balayeva,E. Yu. Akhmedov
The HPLC method of thymol quantification has been developed for the combined medicine – “Kalinol plus” syrup (produced by “Azerpharm LTD”), which consists of the brotherwort (Thymus serpyllum) extract, sugar syrup, potassium bromide and 80% ethanol. The o... see more
V. S. Kyslychenko,V. Yu. Kuznietsova,Yu. S. Kolisnyk,N. A. Sushchuk
The results of the anatomical study of shepherd's purse (Capsella bursa-pastoris L.) herb are presented in the article. The main diagnostic features have been identified. The preparations were studied by a “LOMO Mikmed 1” light microscope at a magnificati... see more
T. V. Upyr,K. S. Tolmacheva,O. M. Koshovyi,A. M. Komissarenko,I. V. Kireev
Ledum palustre shoots (Cormus Ledi palustri) hase long been used as an antispasmodic, diuretic, diaphoretic, disinfectant, anti-inflammatory, sedative and antitussive remedy in folk medicine. The most studied are terpene compounds, they are component of e... see more
M. A. Komissarenko
The qualitative composition and quantitative content of volatile substances of cowberry leaves (Vaccinium vitis-idaea L.) has been studied by gas chromatography. Identification of substances has been performed based on comparison of the mass spectra obtai... see more
L. V. Lenchyk,A. A. Sichkar,Ye. V. Gladukh,V. S. Kyslychenko
The composition of tablets with cherry soft extract codenamed "Fructopad" has been developed and technological properties of tablet granules and crash resistance and friability of tablets have been determined. Based on modern approaches to standardization... see more
B. T. Kudrik,O. I. Tikhonov,O. S. Shpychak
The physical, physicochemical and pharmacotechnological properties of active pharmaceutical ingredients and their mixtures with the excipients of “Api-Immuno-Vit” capsules with the immunomodulatory action based on bee bread and powdered honey have been st... see more
I. O. Omelchenko,T. G. Yarnykh,G. I. Borschevskyi
The choice of exipients for sublingual tablets “Corvalol” by the method of direct compression was based on the study of the physical properties of the tablet formulations. Three models of tablet formulations were analyzed. It is found that the optimal exi... see more
O. Ye. Strus,O. G. Geyderikh,L. F. Silaeva
Sapropel muds have a different chemical composition and provide the anti-inflammatory, desensitizing effect, they protect the skin from destructive effects of free radicals, give the skin elasticity, firmness and freshness, moisten the horny layer of the ... see more
O. O. Shmalko,L. I. Vishnevskaya,Yu. G. Piskovatskiy,V. A. Megalinskij
Among the most dangerous diseases of the hepatobiliary system (GBS), and gall bladder there are chronic and acute viral hepatites, cirrhosis and fibrosis of the liver, cholestases, cholecystitis, fatty liver, etc. Despite the large number of diseases, as ... see more
M. V. Balynska
In the article the results of a comprehensive expert evaluation of drugs for the treatment of viral diarrhea (VD) in children as an important stage in the development of regulatory socioeconomic lists (SEL) are presented. In particular the results of calc... see more
D. A. Lega,N. I. Filimonova,I. A. Zupanets,S. K. Shebeko,V. P. Chernykh,L. A. Shemchuk
The search and development of new bioactive compounds, possessing antimicrobial, anti-inflammatory and analgesic activities, are the topical issues of current medicinal chemistry. 2,1-Benzothiazine 2,2-dioxides condensed with 2-amino-3-R-4-(het)aryl-4H-py... see more
N. M. Derkach,S. Yu. Shtrygol’,Yu. B. Laryanovska,S. A. Grashenkova
The intestinal diseases of bacterial aetiology are characterized by high prevalence and a severe course, especially at a young age, concomitant immunity suppression or chronic diseases of the gastrointestinal system. Therefore, it is expedient to search f... see more
L. Bulyga,Ya. Butko,Yu. Laryanovska
The search for new drugs to treat purulent wounds is one of the urgent problems of modern medicine. Most local wound healing drugs at the pharmaceutical market of Ukraine do not meet all modern medical and biological requirements for effective treatment o... see more
S. V. Vlasov,V. P. Chernykh
An effective method for synthesis of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidine-4(3H)-thione starting from the corresponding 4-oxo analog has been developed. For the chemical diversity enlargement the alkylation of 6-(1H-benzimidazol-2-yl)-5... see more