17 articles in this issue
L. D. Grytsan
After a brief review of the basic ideas and principles of the method of physicochemical analysis, its advantages and drawbacks, a number of its applications in pharmaceutical science and technology has been considered. The diagrams of fusion, boiling and ... see more
K. Yu. Krolenko,S. V. Vlasov,O. D. Vlasova,I. O. Zhuravel
By the interaction of the substituted aryl isocyanates with the series of 3-arylmethyl-1,3,7-triazaspiro[ 4.4]nonane-2,4-diones in the propanol-2 medium the series of the substituted aryl amides of 3-arylmethyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7-car... see more
V. O. Zubkov,N. I. Ruschak,M. M. Suleiman,A. O. Devyatk?na,I. S. Gritsenko
Due to a global increase of microbial resistance to antimicrobial drugs the search for new antibiotics is vital for modern medicinal chemistry. 3-Quinolin-4-one propanoic acids have the molecular similarity with fluoroquinolone antibiotics and are prospec... see more
M. Ya. Smolinska,I. Ya. Kotsiumbas,G. Yu. Teslyar,M. V. Yurkevych
The paper presents the results of developing the method for quantitative determination of benzocaine and penicillin-G-procaine in seven combined medicines and veterinary medicinal products of different dosage forms – ointments, suppositories and tablets. ... see more
O. O. Stremoukhov,O. M. Koshovyi,O. I. Zalyubovska
Using chromato-mass-spectrometry the analysis of the qualitative composition and the quantitative content of organic and fatty acids in Vaccinium uliginosum leaves has been conducted. The analysis of methyl esters of fatty and organic acids has been perfo... see more
O. V. Stadnichenko,Yu. M. Krasnopolsky,T. G. Yarnykh
The fight against cancer diseases is one of the most urgent problems of modern pharmacy. One of the basic standards of treatment is surgery in order to remove tumours with chemotherapeutic agents for suppression of disease manifestations. One of the ways ... see more
M. Fedorovska,N. Polovko
The article presents the study results of developing the optimal composition for the base of the maskgel for treating telogen effluvium. The effect of the preservative potassium sorbate in different concentrations (from 0.1% to 0.3%) on the pH and structu... see more
O. ?. Shmalko,L. I. Vyshnevska,V. A. Megalinskyi
Syrups obtained on the basis of the medicinal plant raw material are of special interest for conducting research despite the presence of their specific flavour characteristics, technology of intermediates, and increased susceptibility to microbial contami... see more
V. A. Khanin,O. M. Kotenko,O. O. Moiseev,O. V. Dorovskyy
There are a number of methods for determination of diclofenac sodium in medicines; however, they all differ by analytical methods involved depending on the drug dosage form. The aim of the study was to develop the universal HPLC-method for determination o... see more
L. S. Petrovska
The article considers the main trends in development of the cosmetic and beauty products market in Ukraine over the past five years. The analysis of indicators of volumes of production, export and import of cosmetic products in natural units and monetary ... see more
M. V. Zarichkova
This article deals with the study of expenditure for social protection in the European Union (EU) and Ukraine, which is the criterion characterising the level of public liability for support of a certain standard of living of the poorest social groups. Du... see more
N. M. Tryschuk,I. V. Kireyev,S. V. Kolisnyk,K. M. Sytnik
The acute toxicity of 17 new derivatives of benzilic acid in outbred mice weighing 20-26 g has been determined. Animals were divided into 68 groups of 5 mice each. Each group of animals received the aqueous solution of the substance under study once orall... see more
I. A. Takhirov,V. Y. Asmetov,T. A. Suleymanov,F. D. Abdulkerimova,M. M. Ganiev,E. Yu. Akhmedov
The aim of the work was to study the antihypoxic action of the biologically active mixtures obtained from Fraxinus excelsior (European ash) growing in Azerbaijan Guba region and Phlomis pungens (Jerusalem sage) from the Nakhichevan Autonomous Republic. Th... see more
O. Yu. Koshova,H. O. Ieryomina,L. O. Perekhoda,Z. G. Yeryomina
The study of the anti-allergic action of hydrobromide 2-[4-(41-chlorophenyl)-2-phenyliminothiazol- 3-yl]-ethanol under the code of 6.6 has been conducted. On the model of anaphylactic shock in guinea pigs it has been found that in the prophylactic adminis... see more
N. M. Derkach,Z. S. Suvorova
This study considers the effect of pH on the specific activity of decamethoxinum substance under experimental conditions. It has been shown that the minimum inhibitory concentration (MIC) of this substance depends on the microorganism species and pH; the ... see more
M. Blazheyevskiy,O. Mozgova
The electrochemical behaviour of hydrogen peroxide (H2O2) has been studied using the alternating current voltammetry with square wave modulation in the potential range of +1.0…–1.0 V on the carbositall electrode as a working and auxiliary electrode (vs Ag... see more