News Of Farmacy  

S. V. Kolisnyk,O. M. Svechnikova,R. I. Kratenko,O. V. Kolisnyk

N-[(2-oxoindolin-3-ylidene)-2-oxiacetyl] amino acids reactive ability was investigated at reversible conditions by studying their acid-base properties in binary dioxane-water (60 volume % of dioxane) solvent at 25°C. The experimental compounds were proven... see more

V. A. Georgiyants,L. O. Perekhoda,I. A. Sych,L. O. Grinevich,O. K. Ryadnykh,A. V. Zhuravel

The group of aryl(heteryl)amides of 5-(4-R)benzyl-1,3,4-oxad?azol-2-il-thioacetic acid has been tested for compliance with the “drug likeness” concept. A number of physical and chemical properties that determine bioavailability according to Lipinski’s Rul... see more

O. Ye. Strus

A diverse composition of sapropels allows to use them successfully in cosmetology. Sapropelic therapeutic muds exhibit the anti-inflammatory and desensitizing effect, protect the body from the damaging effects of free radicals, slow down the aging process... see more

L. P. Savchenko,M. O. Khmelyova,O. A. Yevtifeeva,V. A. Georgiyants

One of the main objectives for drug manufacturers is to study stability, which is the quality factor for any drug. The requirements of stability are imposed to the extemporaneous medicines too. The Guide for the Compounding Practitioner (USA) contains art... see more

O. A. Rukhmakova,T. G. Yarnykh

There are some available synthetic drugs of the foreign origin among symptomatic nasal medicines at the current pharmaceutical market. Most of them are produced in the form of drops or sprays, and it causes short duration of action of these drugs. Nowaday... see more

V. S. Kucherenko,Sv. M. Kovalenko,I. I. Baranova

Particular attention when developing drugs is paid to the choice of the rational technology. The technological process is an important aspect affecting the quality and stability of a drug, and should consist of a system of interconnected and evidence-base... see more

A. O. Drozdova

The foaming ability of some surfactants, namely such parameters as the height of the foam column and foam stability, has been studied. It has been found that in solutions with one surfactant there is no specific dependence between the foam height and foam... see more

A. V. Kabachna,E. V. Shelkova,O. G. Kabachnyi

The growth of expenses on drug supply in healthcare requires effective methods for their analysis in the specific healthcare institutions. On the example of a conditional healthcare institution an integrated ABC/VEN-analysis of the expenses on the drug su... see more

I. V. Bondareva

Today, a high degree of uncertainty and instability of the external environment determines the growing importance of adaptation of modern organizations to the new realities. For effective functioning of manufacturing pharmaceutical enterprises it is neces... see more

V. M. Nazarkina,O. A. Nemchenko

It has been shown that nowadays pharmaceutical provision of the population is a complex integration system that combines pharmaceutical care, pharmaceutical services, the process of drug supply and professional pharmacy practice. The content of such conce... see more

O. V. Posylkina,V. G. Kotlarova,Yu. Ye. Novitska

The article has proven that the use of the traditional approach to setting the drug stock level in pharmacy distribution can lead to determination of the level of money immobilized for stock making and does not take into account the needs, expectations an... see more

A. O. Pryskoka,A. V. Rudenko,L. S. Reznichenko,T. G. Gruzina,Z. R. Ulberg,I. S. Chekman

Silver nanoparticles possess a high potential as an antimicrobial substance against a wide spectrum of bacteria, including antibiotic-resistant strains. Antimicrobial properties of silver nanoparticles with 30 nm in diameter synthesized according to the o... see more

Yu. V. Sokolov

A comparative study of efficiency of injection and oral forms of ivermectin has been conducted. The research results indicate that efficiency of drugs with ivermectin against endoparasites is very high and reaches 100%. The exception is Oesophagostomum de... see more

S. V. Fedorov

Chronic heart failure (HF) is a highly prevalent chronic pathological condition with high morbidity and mortality rates. The cost for HF treatment is 2% of the national health expenditures each year. Fibronectin (Fn) has a crucial role in the process of t... see more

M. Yu. Golik,M. A. Komissarenko,S. G. Leonova,T. P. Osolodchenko

The intensive use of antibiotics in patient care institutions often without determining specificity and sensitivity to them leads to more rapid development of resistance to pathogens of nosocomial infections; that is why it is one of the urgent problems o... see more

O. V. Sevryukov,V. A. Volkovoy,S. V. Kolisnyk,K. M. Sytnik

It has been experimentally proven that with the intraperitoneal way of introduction of Dezapur the maximum tolerated dose for mice is 2000 mg/kg, the least toxic dose – 1000 mg/kg, the median lethal dose – 3000 mg/kg. When the dose of 3500 mg/kg was intro... see more

V. S. Klevanova,S. D. Trzhetsynskiy,N. S. Fursa

Atherosclerosis is recognized as “non-infectious pandemic of the XXI-th century”. There is a wide range of drugs for correction of hyperlipidemia, as well as for the primary and secondary prevention of athe-rosclerosis complications. However, all known li... see more