6 articles in this issue
Veronika Koutná, Martin Jelínek, Marek Blatný and Tomáš Kepák
This longitudinal study aims to analyze predictors of posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG) among gender, age, objective factors of the disease and its treatment, family environment factors and negative emotionality. The samp... see more
Laura Di Blasio, Paolo A. Gagliardi, Alberto Puliafito and Luca Primo
Dissecting the cellular signaling that governs the motility of eukaryotic cells is one of the fundamental tasks of modern cell biology, not only because of the large number of physiological processes in which cell migration is crucial, but even more so be... see more
David Gyori, Tamara Chessa, Phillip T. Hawkins and Len R. Stephens
Phosphoinositide 3-kinases (PI3Ks) are a diverse family of enzymes which regulate various critical biological processes, such as cell proliferation and survival. Class (I) PI3Ks (PI3Ka, PI3Kß, PI3K? and PI3Kd) mediate the phosphorylation of the inositol r... see more
Yutaka Yonemura, Yoshio Endo, Emel Canbay, Yang Liu, Haruaki Ishibashi, Akiyoshi Mizumoto, Masamitu Hirano, Yuuki Imazato, Nobuyuki Takao, Masumi Ichinose, Kousuke Noguchi, Yan Li, Satoshi Wakama, Kazuhiro Yamada, Koutarou Hatano, Hiroshi Shintani, Hiroyuki Yoshitake and Shun-ichiro Ogura
In the past, peritoneal metastasis (PM) was considered as a terminal stage of cancer. From the early 1990s, however, a new comprehensive treatment consisting of cytoreductive surgery and perioperative chemotherapy has been established to improve long-term... see more
Daisuke Obinata, Kenichi Takayama, Satoru Takahashi and Satoshi Inoue
Prostate cancer is the second leading cause of death from cancer among males in Western countries. It is also the most commonly diagnosed male cancer in Japan. The progression of prostate cancer is mainly influenced by androgens and the androgen receptor ... see more
Bilal Rahim and Ruth O’Regan
Androgen receptor (AR, a member of the steroid hormone receptor family) status has become increasingly important as both a prognostic marker and potential therapeutic target in breast cancer. AR is expressed in up to 90% of estrogen receptor (ER) positive... see more