Journal title

Cells  

ISSN: 2073-4409    frecuency : 4   format : Electrónica

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Volume 7 Number 11 Part November Year 2018

30 articles in this issue 

Tawfeek Altawaty, Lulu Liu, Hongyong Zhang, Cong Tao, Shaohua Hou, Kui Li and Yanfang Wang

The essential requirement of the lymphotoxin beta receptor (LTβR) in the development and maintenance of peripheral lymphoid organs is well recognized. Evidence shows that LTβR is involved in various cellular processes; however, whether it plays ... see more

 

Friederike K. Kosyna and Reinhard Depping

Nuclear transport receptors of the karyopherin superfamily of proteins transport macromolecules from one compartment to the other and are critical for both cell physiology and pathophysiology. The nuclear transport machinery is tightly regulated and essen... see more

 

Claudia Ricci, Carlotta Marzocchi and Stefania Battistini

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal disorder characterized by the progressive loss of motor neurons in the cerebral cortex, brain stem, and spinal cord. Sporadic ALS form accounts for the majority of patients, but in 1–13.5... see more

 

Michael Mederos y Schnitzler, Thomas Gudermann and Ursula Storch

Transient receptor potential classical or canonical 4 (TRPC4) and TRPC5 channels are members of the classical or canonical transient receptor potential (TRPC) channel family of non-selective cation channels. TRPC4 and TRPC5 channels are widely accepted as... see more

 

Yoshihiko Kuchitsu and Mitsunori Fukuda

Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes. It localizes to late endosomes and lysosomes and has multiple functions in the autoph... see more

 

Kwanhyeong Kim, Juyeon Lee, Hyunji Moon, Sang-Ah Lee, Deokhwan Kim, Susumin Yang, Dae-Hee Lee, Gwangrog Lee and Daeho Park

Ephexin4 is a guanine nucleotide-exchange factor (GEF) for RhoG and is involved in various RhoG-related cellular processes such as phagocytosis of apoptotic cells and migration of cancer cells. Ephexin4 forms an oligomer via an intermolecular interaction,... see more

 

Ibrahim González-Marrero, Luis G. Hernández-Abad, Emilia M. Carmona-Calero, Leandro Castañeyra-Ruiz, José A. Abreu-Reyes and Agustín Castañeyra-Perdomo

Aquaporin 1 (AQP1) and aquaporin 4 (AQP4) have been identified in the eye as playing an essential role in the formation of the aqueous humor along with the Na+/K+ ATPase pump. Different authors have described the relationship between blood pressure, aqueo... see more

 

Marcelo Ozu, Luciano Galizia, Cynthia Acuña and Gabriela Amodeo

Aquaporins (AQPs) function as tetrameric structures in which each monomer has its own permeable pathway. The combination of structural biology, molecular dynamics simulations, and experimental approaches has contributed to improve our knowledge of how pro... see more

 

Ita Novita Sari, Lan Thi Hanh Phi, Nayoung Jun, Yoseph Toni Wijaya, Sanghyun Lee and Hyog Young Kwon

The Hedgehog (Hh) pathway is a signaling cascade that plays a crucial role in many fundamental processes, including embryonic development and tissue homeostasis. Moreover, emerging evidence has suggested that aberrant activation of Hh is associated with n... see more

 

Tamar Segal, Mali Salmon-Divon and Gabi Gerlitz

H3K9me3, H3K27me3, and H4K20me1 are epigenetic markers associated with chromatin condensation and transcriptional repression. Previously, we found that migration of melanoma cells is associated with and dependent on global chromatin condensation that incl... see more

 

Daniela Ribeiro, Marisa Freitas, Sílvia Rocha, José L. F. C. Lima, Félix Carvalho and Eduarda Fernandes

In neutrophils, intracellular Ca2+ levels are regulated by several transporters and pathways, namely SERCA [sarco(endo)plasmic reticulum Ca2+-ATPase], SOCE (store-operated calcium entry), and ROCE (receptor-operated calcium entry). However, the exact mech... see more

 

Juhyung Lee and Yihong Ye

Protein secretion in general depends on signal sequence (also named leader sequence), a hydrophobic segment located at or close to the NH2-terminus of a secretory or membrane protein. This sequence guides the entry of nascent polypeptides into the lumen o... see more

 

Rosanna Avola, Adriana Carol Eleonora Graziano, Giovanna Pannuzzo and Venera Cardile

The development in digital screen technology has exponentially increased in the last decades, and many of today’s electronic devices use light-emitting diode (LED) technology producing very strong blue light (BL) waves. Long-term exposure at LED-BL ... see more

 

Shuyuan Wang, Wencan Wang, Qianqian Meng, Shunheng Zhou, Haizhou Liu, Xueyan Ma, Xu Zhou, Hui Liu, Xiaowen Chen and Wei Jiang

Autophagy is a complex cellular digestion process involving multiple regulators. Compared to post-translational autophagy regulators, limited information is now available about transcriptional and post-transcriptional regulators such as transcription fact... see more