10 articles in this issue
Xiang Lu and Karima Djabali
The mammalian nuclear lamina proteins—prelamin A- and B-type lamins—are post-translationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxy-terminal CAAX (C, cysteine; a, aliphatic amino acid; X, any amino acid... see more
Valentin Pitzen, Sophie Askarzada, Ralph Gräf and Irene Meyer
-
Verónica Chico, Sara Puente-Marin, Iván Nombela, Sergio Ciordia, María Carmen Mena, Begoña Carracedo, Alberto Villena, Luis Mercado, Julio Coll and María Del Mar Ortega-Villaizan
Primitive nucleated erythroid cells in the bloodstream have long been suggested to be more similar to nucleated red cells of fish, amphibians, and birds than the red cells of fetal and adult mammals. Rainbow trout Ficoll-purified red blood cells (RBCs) cu... see more
Nicolette N. Houreld, Sandra M. Ayuk and Heidi Abrahamse
Diabetes affects extracellular matrix (ECM) metabolism, contributing to delayed wound healing and lower limb amputation. Application of light (photobiomodulation, PBM) has been shown to improve wound healing. This study aimed to evaluate the influence of ... see more
Michael P. Koonce and Irina Tikhonenko
Antje Banning, Tanja Babuke, Nina Kurrle, Melanie Meister, Mika O. Ruonala and Ritva Tikkanen
Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and flotillin-... see more
Yu-Hong Jiang, Ying Mao, Yi-Na Lv, Lei-Lei Tang, Yi Zhou, Huan Zhong, Jun Xiao and Jin-Peng Yan
Toshimitsu Hiragi, Yuji Ikegaya and Ryuta Koyama
Microglia are the resident immune cells in the brain that constitute the brain’s innate immune system. Recent studies have revealed various functions of microglia in the development and maintenance of the central nervous system (CNS) in both health and di... see more
Daniel Kummer and Klaus Ebnet
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development. These include processes such as infl... see more
Quanguo He, Jun Liu, Jing Liang, Xiaopeng Liu, Wen Li, Zhi Liu, Ziyu Ding and Du Tuo
The blood–brain barrier (BBB) is a critical biological structure that prevents damage to the brain and maintains its bathing microenvironment. However, this barrier is also the obstacle to deliver beneficial drugs to treat CNS (central nervous system) dis... see more