10 articles in this issue
Anna Meiliana,Andi Wijaya
BACKGROUND: Statins have been used for around three decades as the primary way to lower cholesterol and reduce the risk of atherosclerosis, but in some groups, statin resistance is common, and the danger of atherosclerosis is still high.CONTENT: Atheroscl... see more
Sadoun Abbas Alsalimi,Idries Muhson Abeed Al-Mashkor,Adnan Jassim Mohammed Al-Fartosy
BACKGROUND: Various biological markers have been proposed to predict subclinical events in subjects with chronic hepatitis B virus (HBV). However, studies regarding chronic HBV infection are still limited. The current study aimed to investigate the relati... see more
Aiman Al-Maathadi,Fardous Karawya,Said Al-Dalaen,Ahmed Aljabali,Anas Satari
BACKGROUND: Titanium dioxide nanoparticles (TiO2 NPs) uptake may primarily cause adverse effects by inducing oxidative stress, resulting in cell damage, genotoxicity, inflammation, and immune response. To date, there are limited studies investigating the ... see more
Septin Kamilia Patinggi,Yuriz Bakhtiar,Selamat Budijitno,Neni Susilaningsih,Udin Bahrudin
BACKGROUND: Researches on plant active substances are conducted to find effective topical drugs for mid dermal burns wound. The 70% hydrolyzed VCO (hVCO) cream has been known to accelerate macroscopic healing of mid dermal burns compared to 30% and 50% hV... see more
Rahmad Mulyadi,Joedo Prihartono,Em Yunir,Dian Anindita Lubis,Reyhan Eddy Yunus
BACKGROUND: One type of thalassemia known as transfusion-dependent thalassemia (TDT) requires a lifelong blood transfusion. Iron overload from prolonged blood transfusions causes nutritional disorders and several organs impairment, including the testicles... see more
Yenny Surjawan,Umi Solekhah Intansari
BACKGROUND: The anti-nuclear antibody immunofluorescence (ANA-IF) test is used for screening of autoantibody presence in patients with suspected autoimmune disease. Positive ANA-IF should be followed-up with extractable nuclear antigens profile (ENA-profi... see more
Muhammad Javedh Iqbal,Diah Rumekti Hadiati,Didik Setyo Heriyanto
BACKGROUND: Early-onset preeclampsia is characterized by higher oxidative stress and apoptosis level than late-onset one. Studies comparing the expression of the Bcl-2 family protein in early and late-onset preeclampsia are still lacking and show inconclu... see more
Sonar Soni Panigoro,Arif Kurniawan,Ramadhan Ramadhan,Ninik Sukartini,Herqutanto Herqutanto,Rafika Indah Paramita,Ferry Sandra
BACKGROUND: Amino acids are important for proliferation and maintenance of tumor cells. Breast cancer patients were found to have significant changes in the number of amino acids, which are assumed to be correlated with the molecular subtypes of breast ca... see more
Oentarini Tjandra,Shirly Gunawan,Johan Johan,Fia Fia Lie,Marcella Erwina Rumawas,Agus Limarta
BACKGROUND: Available medication for pain and joint stiffness release in osteoarthritis (OA) often gives considerable side effects. Undenatured type II collagen (UC-II) has been considered as a treatment for OA for its ability to prevent the progress of a... see more
Alvina Alvina,Suzanna Immanuel,Dante Saksono Harbuwono,Frans Dhyanagiri Suyatna,Alida Harahap,Joedo Prihartono,Pusparini Pusparini
BACKGROUND: 25(OH)D level is correlated with insulin secretion and tissue sensitivity to insulin. Administration of vitamin D supplements may reduce tissue resistance to insulin in type 2 diabetes mellitus (T2DM), but a number of studies found conflicting... see more