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3.746  Articles
1 of 376 pages  |  10  records  |  more records»
Objectives: To assess the association of bronchoalveolar lavage fluid (BALF) a-SMA and ß-catenin levels and the severity of pneumonia.Methods: The records of patients with severe pneumonia treated in our hospital from June 2019 to June 2020 were selected.... see more

Objective: The aim of this study is to investigate in vitro effects of an antihelminthic drug niclosamide on human ovarian carcinoma cell line OVCAR-3. Methods: MTT assay was applied to investigate the cytotoxic effects of niclosamide on the cells. ß-cate... see more

Breast cancer is the second most common cancer among women worldwide. The Wnt–ß-catenin pathway appears to be deregulated in most can­cer cells including breast cancer. The role of zerumbone, the active sesquiter­pene from Zingiber zerumbet Roscoe, on the... see more

Recently, various immunosuppressant drugs have been shown to induce hair growth in normal hair as well as in alopecia areata and androgenic alopecia; however, the responsible mechanism has not yet been fully elucidated. In this study, we investigate the i... see more

Increasing evidences show that XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6) was upregulated and involved in tumor growth in several tumor types. However, the correlation of XRCC6 and human osteosarcoma (OS) is still unkno... see more

The aberrant activation of Wnt signaling has been implicated in a variety of human cancers, including gastric cancer. Given the current hypothesis that cancer arises from cancer stem cells (CSCs), targeting the critical signaling pathways that support CSC... see more

The objective of this study is to evaluate of rice bran mineral extract (RBM) increases the expression of anagen-related molecules in human dermal papilla (DOCs). Four treatment groups were established to evaluate the efficacy of RBM, including a negative... see more

The present study demonstrates the effects of triptolide, one of the constituents from Tripterygium wilfordii, on the self-renewal capacity of human hepatocellular carcinoma. The investigation revealed that triptolide markedly prevented the proliferation ... see more

BACKGROUND: The aberrant activation of Wnt signalling pathway may be a common denominator for the development of thyroid tumorigenesis. It was announced that the loss of E-cadherin rather than ß-catenin mutation represents a crucial event in determining t... see more

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