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20.743  Articles
1 of 2.075 pages  |  10  records  |  more records»
Somatic mutations in 3′-untranslated regions (3′UTR) do not alter amino acids and are considered to be silent in cancers. We found that such mutations can promote tumor progression by altering microRNA (miRNA) targeting efficiency and conseque... see more

Previous studies showed that mutations in the SARS-CoV-2 ORF3a protein can influence viral pathogenesis. Therefore, it is necessary to observe mutations, especially in the functional domain of the protein. We observed the presence of mutations in the ORF3... see more

Epigenetics or imprinting refers to the process of ‘chemically’ marking the central A, C, G, T double-stranded DNA code. In the past several decades a deeper understanding has been gained of a wide range of mechanisms that have been invoked in biology for... see more

Noncanonical WNT pathways function independently of the ß-catenin transcriptional co-activator to regulate diverse morphogenetic and pathogenic processes. Recent studies showed that noncanonical WNTs, such as WNT5A, can signal the degradation of several d... see more

Objective: To identify the genetic variants in the CYP1B1 gene associated with Primary Congenital Glaucoma (PCG) and to predict its pathological effect.Method: A descriptive study was conducted in the time period of nine months (September 2021-May 2022) a... see more

Romanchuk A. P., Guziy O. V., Podgorna V. V., Glushchenko M. M. «?????????» ?????? ??????????? ??????’? ????????? ???????? ???? ? ?????????? ????????? ??????????????????? ??????? = "Safe" level of somatic health in indicators regulation of cardiorespirato... see more

Introduction. Volleyball is one of the most popular sports in Poland. In recent years, there is a growing interest in this discipline among young people. It is important for researchers and trainers to find the factors that determine the achievement of hi... see more

Purpose. The educational process requires a commitment from officer cadets to develop and maintain physical fitness as a basis for implementing various training tasks. This process is often associated with numerous overloads and musculoskeletal injuries i... see more

An enhancer trap system is an insertional mutagenesis based upon gene expression, instead of gene knock-out, so its insertion in genome is  expected not linked to any dramatic changes in plant phenotypes. Gene  knock-out, leading to lossof- func... see more

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