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935.087  Articles
1 of 93.510 pages  |  10  records  |  more records»
Condensation of bifunctional 1-aminoisoindole with bis-electrophilic methyl 4-chloro-3-oxobutanoate undergoes regioselectively to afford 2-(chloromethyl)-2-hydroxy-2,6-dihydro­pyrimido[2,1-a]isoindol-4(3H)-one. The structure of the reaction product was un... see more

The nucleophilic substitution of the nitro group of 4-alkyl-6-nitro-4,7-dihydro-1,2,4-triazolo[5,1-c][1,2,4]triazine-7-ones on the example of interactionwith morpholine was studied. It is established that under the action of excess cycloalkylimine at room... see more

The tautomerism of 4-hydrazinoquinazoline and its derivatives was investigated. Geometry and thermodynamic parameters were computed theoretically using Gaussian 03 software. All calculations were performed at the MP2 level of theory using the standard 6-3... see more

Derivatives of piperazin-1-dithiocarbamates 4-aniline piperidine were synthesized and their structures were identified by elemental analysis IR, NMR and mass spectroscopy. The biological activity of the synthesized derivatives of dithiocarbamates was inve... see more

Recently, mental health is one of the most serious problems faced by all countries due to at least every fourth person have such problems at any given period of life. In European region, prevalence of mental disorders is rather high. According to the WHO ... see more

Screening studies have revealed that the new derivate of 4-[4-oxo-4H-quinazoline-3-yl] benzoic acid (compound PC-66) possess significant antinociceptive and weakly expressed anti-inflammatory and antipyretic activity on different models of pain and inflam... see more

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