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1.106.879  Articles
1 of 110.689 pages  |  10  records  |  more records»
Condensation of bifunctional 1-aminoisoindole with bis-electrophilic methyl 4-chloro-3-oxobutanoate undergoes regioselectively to afford 2-(chloromethyl)-2-hydroxy-2,6-dihydro­pyrimido[2,1-a]isoindol-4(3H)-one. The structure of the reaction product was un... see more

The tautomerism of 4-hydrazinoquinazoline and its derivatives was investigated. Geometry and thermodynamic parameters were computed theoretically using Gaussian 03 software. All calculations were performed at the MP2 level of theory using the standard 6-3... see more

In order to establish the formation of supramolecular inclusion complexes of 1-(2-ethoxyethyl)-4-(hexyne-1-yl)-4-benzoyloxypiperidine with ß-cyclodextrin and their structures, 1H and 13C NMR spectra of 1-(2-ethoxyethyl)-4-(hexyne-1-yl)-4-benzoyloxypiperid... see more

The nucleophilic substitution of the nitro group of 4-alkyl-6-nitro-4,7-dihydro-1,2,4-triazolo[5,1-c][1,2,4]triazine-7-ones on the example of interactionwith morpholine was studied. It is established that under the action of excess cycloalkylimine at room... see more

Derivatives of piperazin-1-dithiocarbamates 4-aniline piperidine were synthesized and their structures were identified by elemental analysis IR, NMR and mass spectroscopy. The biological activity of the synthesized derivatives of dithiocarbamates was inve... see more

Screening studies have revealed that the new derivate of 4-[4-oxo-4H-quinazoline-3-yl] benzoic acid (compound PC-66) possess significant antinociceptive and weakly expressed anti-inflammatory and antipyretic activity on different models of pain and inflam... see more

The advanced study of the analgesic activity of N-(3-pyridylmethyl)-4-hydroxy-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide selected by the results of the primary pharmacological screening as the leading structure has revealed a significant chan... see more

The aim of this preliminary research was to synthesize derivatives of eugenol such as 4-allyl-2-methoxy-6-nitrophenol (2) and 4-allyl-2-methoxy-6-aminophenol (3). The result could be used as a reference on the transformation of eugenol to its derivatives.... see more

Synthesis, characterization and adsorption test of poly-tetra-p-propenyl-tetrahydroxycalix[4]arene for cadmium ion had been done. The synthesis was carried out in five steps, which were (1) synthesis of p-t-butylcalix[4]arene from p-t-butylphenol, (2) deb... see more

1 of 110.689 pages  |  10  records  |  more records»