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2.835  Articles
1 of 285 pages  |  10  records  |  more records»
Objective: To evaluate the association of miR-196a rs11614913 C/T genetic variation and its target gene annexin A1 mRNA expression with breast cancer risk in Pakistani female ethnicities.Methods: This case control study, conducted from March 2017 to Novem... see more

AIM: To investigate the relationship between the polymorphism of related gene loci of miRNAs regulated fibrinopeptide A and schizophrenia. Lay the foundation for the aetiology of schizophrenia.METHODS: Adapt to the phase match of sex and age case-control ... see more

Somatic mutations in 3′-untranslated regions (3′UTR) do not alter amino acids and are considered to be silent in cancers. We found that such mutations can promote tumor progression by altering microRNA (miRNA) targeting efficiency and conseque... see more

Background: Natural killer (NK) cells play a role in pathogenesis of endometriosis. Lower expressions of NK cells receptor group 2D (NKG2D) ligands inhibits cytotoxic activity of NK cells; a common immunity avoidance mechanism in neoplasms. Literatures ha... see more

The diversity of lactic acid bacteria (LAB) present during the manufacture of traditional fermented buffalo milk from West Sumatra, known as dadih, was studied via a culture-independent approach using terminal-restriction fragment length polymorphism (T-R... see more

A polymorphism, rs4245739, has been associated with susceptibility of several cancers including ER-negative breast cancer.  Rs4245739 is located at the 3’UTR of MDM4 gene, an oncogene that negatively regulates p53. The polymorphism has been associate... see more

It has been known that there are differences in response to medications both in terms of clinical activity and side effects. Among all influencing factors, genetic variation has been considered to play a crucial part. By genetic investigation, the differe... see more

It has been known that there are differences in response to medications both in terms of clinical activity and side effects. Among all influencing factors, genetic variation has been considered to play a crucial part. By genetic investigation, the differe... see more

DOI: 10.15414/afz.2015.18.04.83–89Received 7. July2015 | Accepted 30. September 2015 | Available online 7. December 2015Two types of molecular markers based on randomly amplified DNA by RAPD-based assay and amplified microRNA bymiRNA-based assay were appl... see more

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