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1.072.805  Articles
1 of 107.281 pages  |  10  records  |  more records»
PurposePenile rehabilitation therapy using phosphodiesterase type 5 inhibitors (PDE5i) is used widely as a first-line therapy in patients with erectile dysfunction (ED) after radical prostatectomy (RP). However, many patients undergoing such therapy still... see more

Background: Spinal cord injury is still a devastating complication after surgical repair of thoracoabdominal aortic pathologies. In this study, we investigated the protective effect of cilostazol, a type III phosphodiesterase inhibitor, against ischemia/r... see more

Objectives: Nitric oxide (NO) is a signaling molecule that mediates mechanical bone loading. Cyclic guanosine 3', 5' monophosphate (cGMP) is a NO-induced effector molecule. The aim of this study was to assess the effect of NO-cGMP pathway on orthodontic t... see more

Wolowiec Lukasz, Banach Joanna, Rogowicz Daniel, Grochowska Magdalena, Zukow Walery, Sinkiewicz Wladyslaw. Inhibitory proproteinowej konwertazy subtylizyny/keksyny 9 nowym, przelomowym narzedziem terapeutycznym w leczeniu dyslipidemii = Proprotein convert... see more

Sotagliflozin (SOTA) is a dual inhibitor of SGLT1 and SGLT2 used in adults with type 1 diabetes. The mechanism of action, based on the inhibition of both the SGLT1 and SGLT2 cotransporters, allows simultaneous increase of glucose excre... see more

Objective: To determine the efficacy and safety of Sodium-glucose cotransporter-2 inhibitors (SGLT2i) use in the Pakistani population.Methods: Retrospective review of initial 100 patients who were prescribed with any agent of the SGLT2i group from July 1,... see more

Sodium-glucose cotransporter 2 (SGTL2) inhibitors, a novel class of glucose-lowering agents, act in an insulin-independent manner by increasing urinary glucose excretion. In addition to reduce hyperglycemia, SGTL2 inhibitor exerts beneficial effects on ca... see more

The incretin hormone glucagon-like peptide 1 (GLP-1), proposed as a new target for the treatment of type 2 diabetes, is rapidly cleaved by dipeptidyl peptidase-IV enzyme (DPP-IV/CD26). DPP-IV inhibitors enhance circulating GLP-1 level, which in turn resul... see more

SGLT-2 inhibitors may be increasingly used in people with type 1 diabetes as new licenses are obtained. These drugs have the potential to improve glycaemic control in people with type 1 diabetes with the added benefit of weight loss, better control of blo... see more

1 of 107.281 pages  |  10  records  |  more records»