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137  Articles
1 of 15 pages  |  10  records  |  more records»
Introduction: Lipids contribute to atherosclerosis and obesity that can lead to different cardiovascular diseases. Statins are hydroxymethylglutaryl reductase inhibitors that effectively lower the cholesterol level. It is widely prescribed in the treatmen... see more

The leading cause of mortality in Ukraine are cardiac and vascular diseases. Hypercholesteremia is an important risk factor for development of cardiovascular disease (CVD). A high preventive efficacy of statins for correction of hypercholesteremia and red... see more

Diseases of the circulatory system are the main cause of disability and premature death in Ukraine. A great number of RCTs and meta-analyses proved high preventive efficiency of statins to reduce the cardiovascular risk. The aim of the study is to analyze... see more

Cardiovascular disease is one of the deadliest diseases in the world. Nowadays, alongside the developments of various medical therapeutic strategies, there is a decreasing trend of cardiovascular mortality. However, this reduction is not adequate and need... see more

Treatment with statins is one of the most effective ways of reducing cardiovascular events in those with diabetes. Many studies containing thousands of subjects with diabetes have demonstrated that statins reduce cardiovascular events when there is no kno... see more

Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which reduces HMG-CoA to mevalonate, the precursor of cholesterol via squalene. Inhibition of HMG-CoA reductase results in a decrease in cholesterol productio... see more

Non-infectious diseases, including hypercholesterolemia, are now ranked top 10 inIndonesia. Statins are inhibitors of HMG-CoA reductase, an enzyme for biosynthesis ofcholesterol in the liver. Statins have been proven to reduce the risk of death due to CHD... see more

Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in patients over the age of 65 years in industrialized countries. Epidemiologic studies suggest that high dietary fat intake is a risk factor for the developme... see more

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