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76  Articles
1 of 9 pages  |  10  records  |  more records»
The range of pessaries at the Ukrainian pharmaceutical market is represented by medicines containing substances of the synthetic origin for the treatment of genital herpes (GH). However, combined drugs with a wide range of pharmacological action and minim... see more

An important issue in modern pharmaceutical practice is the creation of new combined medicines for topical treatment of genital herpes.Aim. To determine the quality indicators and study the stability of developed pessaries with acyclovir and essential oil... see more

The range of pessaries at the Ukrainian pharmaceutical market is represented by medicines containing substances of the synthetic origin for the treatment of genital herpes (GH). However, combined drugs with a wide range of pharmacological action and minim... see more

An important issue in modern pharmaceutical practice is the creation of new combined medicines for topical treatment of genital herpes.Aim. To determine the quality indicators and study the stability of developed pessaries with acyclovir and essential oil... see more

Acyclovir (ACV) is an antiviral drug, used for treatment of herpes simplex virus infections with an oral bioavailability of only 10 to 20 % (limiting absorption in GIT to duodenum and jejunum),half-life about 3 hrs, soluble at acidic pH (pKa 2.27) and dis... see more

Acyclovir is an antiviral drug, belonging to the deoxyguanosine family, widely prescribed for the treatment of herpes simplex viral infections, as well as in the treatment of herpes zoster (shingles). Oral bioavailability of acyclovir is very low (10–20%)... see more

The aim of the present study was to develop acyclovir (ACV) ocular drug delivery systems of bovine serum albumin (BSA) nanoparticles as well as to assess their in vivo transcorneal permeability. The ACV-loaded nanoparticles with 4 % and 8 % drug loading w... see more

The aim of this research was to enhance the flux of transdermal drug delivery by using penetration enhancers DMSO. Skin penetration enhancers have been used to improve bioavailability and increase the range of drugs for which topical and transdermal deliv... see more

The aim of this study was to investigate the effect of DMSO on the permeation of acyclovir in the form of topical gel formulations. Different formulations were prepared containing carbopol 934P, acyclovir (1 % w/w) and selected concentration of DMSO (0 to... see more

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