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1.609.009  Articles
1 of 160.902 pages  |  10  records  |  more records»
Substantial evidence suggests that mutated voltage-gated L-type Ca2+ channel subunit CaV1.2 (CACNAIC) is involved in pathophysiology of autism spectrum disorder (ASD), as exemplified by recent findings that mutated CACNAIC and other L-type Ca2+ channels p... see more

Tumor treating fields (TTFields) represent a novel FDA-approved treatment modality for patients with newly diagnosed or recurrent glioblastoma multiforme. This therapy applies intermediate frequency alternating electric fields with low intensity to the tu... see more

Upon stimulation with agonists and shear stress, the vascular endothelium of different vessels selectively releases several vasodilator factors such as nitric oxide and prostacyclin. In addition, vascular endothelial cells of many vessels regulate the con... see more

Facilitation of cardiac L-type Ca2+ current (ICaL) by high stimulation rates or by depolarizing prepulses is characterized by an increase in the fast inactivation time constant (tfast) of ICaL. To explain this phenomenon, mechanisms related to calcium-dep... see more

Diabetes Mellitus continues to be a world public health problem, having a cascade of complications generated by the oxidative Stress induced by the hyperglycaemia. Our aim was to observe the Hippophaea rhamnoides extract involvement in insulin release via... see more

Objective To investigate the epigenetic mechanism of the voltage-gated L-type Ca2+ channel (LTCC) and the large-conductance Ca2+-activated K+ channel (BKCa) function in mesenteric arterial myocytes improved by regular aerobic exercise in hypertension.Meth... see more

The study investigates the effect of copper ions and pH of external solution on intracellular calcium homeostasis and lipid peroxidation in winter wheat roots. Experiment was carried out with winter wheat. Sterile seeds were germinated in Petri dishes on ... see more

Timothy Syndrome (TS) arises from a point mutation in the human voltage-gated L-type Ca2+ channel (Cav1.2). TS is associated with cardiac arrhythmias and sudden cardiac death, as well as congenital heart disease, impaired cognitive function, and autism sp... see more

Objective To investigate the effect of exercise during pregnancy on L-type Ca2+ (CaV1.2) channel in mesenteric artery from spontaneously hypertensive rats (SHR) offspring.Methods Female (11 weeks old) and male (12 weeks old) SHR, female (11 weeks old) and... see more

1 of 160.902 pages  |  10  records  |  more records»