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1.531  Articles
1 of 154 pages  |  10  records  |  more records»
The immunological and biochemical changes caused by pregnancy may uncover new aspects of immune tolerance, applicable in physiological and pathological contexts, and show up new therapeutic strategies for improving pregnancy outcomes. Isoimmune conflict i... see more

A lot of experiments in human and animals evidenced that the exposure to various stressors, but also tumor development can alter systemic redox homeostasis by stimulation of oxidants production or/and suppression of some antioxidant/reparatory systems. Ou... see more

Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell. This protein is encoded by the CTNS gene which is defective in the lysosomal storage disorder, cystinos... see more

The article is devoted to the mechanisms of regulation of redox processes in cells, a review of the Keap1 / Nrf2 / ARE redox-sensitive signaling system as a fundamental pathway that plays a key role in maintaining cellular redox homeostasis under stressfu... see more

Common buckwheat is a significant culture in Ukraine, whose importance for food security has increased in recent decades. An important biological feature of buckwheat is the ability of the crop to grow on poor and especially acidic soils. Common buck... see more

Paper description:Ibogaine, administered as a single oral dose (1-25 mg/kg body weight) is used as an addiction-interrupting agent.We examined the in vivo effect of a single per os dose of ibogaine (1 or 20 mg/kg) on hepatic and erythrocyte antioxidant de... see more

Paper description:Ibogaine in vivo induces liver glycogen depletion, provokes mild oxidative stress and activates antioxidant enzymes.We examined the in vivo effects of a single per os dose of ibogaine (1 or 20 mg/kg) on the morphology and antioxidative s... see more

Some of the main electron carriers in the metabolism are mono- or dinucleotides and they play crucial roles in maintaining a balanced redox homeostasis of cells, and in coupling many anabolic and catabolic reactions. Altered cellular redox status can be a... see more

Iron is an essential element for the growth and proliferation of cells. Cellular iron uptake, storage, utilization and export are tightly regulated to maintain iron homeostasis. However, cellular iron metabolism pathways are disturbed in most cancer cells... see more

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