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55.027  Articles
1 of 5.504 pages  |  10  records  |  more records»
Background & Objective: Child & adolescent mental health needs to be considered as an integral component of overall health, however significant gaps exist in service provision especially inpatient services in Pakistan. The paper presents the characteristi... see more

The ongoing monitoring of the inpatient stage of treatment is the necessary condition for improving the quality of pharmacotherapy of such costly diseases as rheumatoid arthritis (RA) and optimizing the costs for its implementation. According to the data ... see more

Low self-esteem is a common feature in Anorexia Nervosa (AN) and has been hypothesised to act as a predisposing, precipitating, and perpetuating factor. The aim of this study was to assess the effectiveness of a Cognitive Behavioural Therapy (CBT)-based s... see more

Introduction: The annual National Diabetes Inpatient Audit (NaDIA) in the UK continues to show a high incidence of insulin errors in patients admitted to hospital with diabetes. New initiatives are urgently required to mitigate this risk.Method: The Joint... see more

Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infection Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infectionObjetivo: caracterizar las particularidades de la dinámica de larespuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatorias por activaciones anómalas de las vías deseñalización y desregulación en los interferones, son mecanismosinvolucrados en la respuesta inmune de esta enfermedad. Estasevidencias justifican el uso de tratamientos inmunosupresorescomo la metilprednisolona en los pacientes con cuadros graves. Larespuesta inmune adaptativa aparece después de las dos semanasde infección, aunque la IgM se detecta desde la primera semana.La respuesta de los linfocitos T es indispensable en la completaeliminación de la infección viral.Conclusiones: el sistema inmune juega un papel importanteen la destrucción del epitelio alveolar y el desarrollo de lossíntomas graves de la COVID-19, de ahí que los tratamientosinmunomoduladores pueden beneficiar a estos pacientes.Palabras clave: COVID-19; coronavirus; respuesta inmune;inmunopatogenia.ABSTRACTObjetivo: to characterize the peculiarities of the dynamics of theimmune response during infection with COVID-19.Development: the immune system plays a role in the pathogenesisof COVID-19, where the neutrophil infiltrate is an important eventduring the disease. The production of proinflammatory cytokinesby abnormal activations of the signaling and dysregulationpathways in interferons are mechanisms involved in the immuneresponse of this disease. These evidences justify the use of immunosuppressive treatments such as methylprednisolone inpatients with severe symptoms. The adaptive immune responseappears after two weeks of infection, although IgM is detectedfrom the first week. The response of T lymphocytes is essential inthe complete elimination of the viral infection.Conclusions: the immune system plays an important role inthe destruction of the alveolar epithelium and the developmentof severe symptoms of COVID-19, hence immunomodulatorytreatments can benefit these patients.Keywords: COVID-19; coronavirus; immune response;immunopathogenesis.

respuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatoria... see more

Background: Psoriasis is a chronic cutaneous T-cell mediated disease, which has been associated with many comorbidities, especially with metabolic disorders such as dyslipidemia, diabetes mellitus, obesity, and metabolic syndrome, many of which are themse... see more

Hypertension is a significant health problem considering the complications it causes. The research objective was to describe hypertensive patients' perceptions of their treatment at the inpatient installation of  RSUD Tamiang Layang in 2019. Quantita... see more

Patients have a significant role in improving their own safety. Their active involvement in planning, providing health services, monitoring, and evaluating treatment can improve health services. This study aims to develop a model of patients’ role in impr... see more

Dobosiewicz Anna Maria, Zmaczynska Teresa, Podhorecka Marta, Zukow Walery. Rola skutecznej komunikacji chory-personel medyczny w procesie leczenia pacjenta hospitalizowanego = The role of effective communication between patient and medical staff in the pr... see more

1 of 5.504 pages  |  10  records  |  more records»