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2.395  Articles
1 of 241 pages  |  10  records  |  more records»
Blue light is a major component of visible light and digital displays. Over-exposure to blue light could cause retinal damage. However, the mechanism of its damage is not well defined. Here, we demonstrate that blue light (900 lux) impairs cell viability ... see more

Neurotrophic factors play key roles in the development and survival of neurons. The potent neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), glial cell-line derived neu... see more

Introduction. Glutamate exitotoxicity plays a leading role in damaging of the visual analyzer of traumatic genesis. As it was shown recently, hydrogen sulfide (H2S) system is involved in the regulation of neurotransmission, ophthalmotonus and retinal inju... see more

Diseases of the retina, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), are major causes of blindness in the industrialized world.  There are 25 million people across the globe, including 6 million in the United Statesal... see more

Introduction. Glutamate exitotoxicity plays a leading role in damaging of the visual analyzer of traumatic genesis. As it was shown recently, hydrogen sulfide (H2S) system is involved in the regulation of neurotransmission, ophthalmotonus and retinal inju... see more

The effect of retinal ablation on qualitative and quantitative changes of calbindin D28k and GABA expression in the contralateral optic tectum was studied in young chicks. Fifteen days old chicks had unilateral retinal ablation and after 7 or 15 days, cal... see more

A flexible multi-electrode array (MEA) with an embedded silicon chip for electrical stimulation of neurons or for recording action potentials has been manufactured and characterized. Possible improvements for medical applications using this novel approach... see more

Retinal vascular endothelial growth factor (VEGF) increased by neovascularization is well known as a pathogenic factor in ocular neovascular diseases. However, it is still unclear how retinal neurons are damaged by VEGF. The aims of this study are to demo... see more

Optic neuropathies, such as glaucoma and Leber’s hereditary optic neuropathy (LHON) lead to retinal ganglion cell (RGC) loss and therefore motivate the application of transplantation technique into disease therapy. However, it is a challenge to direct the... see more

1 of 241 pages  |  10  records  |  more records»