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2.195.976  Articles
1 of 219.599 pages  |  10  records  |  more records»
The synthesis of a series of new 4-amino-5-alkyl-1,2,4-triazole(4H)-3-yl thioacetanilides and 4-pyrrolyl-5-alkyl-1,2,4-triazole(4H)-3-yl thioacetanilides has been described in the article. The key intermediates – 4-amino-5-alkyl-3-mercapto-1,2,4-triazoles... see more

The role of the structural modification of 1,4-benzodiazepine systems with dialkylamino groups previously used successfully for a number of important derivatives possessing a complex of specific biological properties has been noted. This paper significant... see more

Synthesis of the series of new 4-phenyl-5-cyclohexyl-1,2,4-triazole(4H)-3-yl thioacetanilides is described. The key intermediate – 4-phenyl-5-cyclohexyl-3-mercapto-1,2,4-triazole(4H) has been synthesized started from cyclohexane carboxylic acid through it... see more

The synthesis of a series of new 4-amino-5-alkyl-1,2,4-triazole(4H)-3-yl thioacetanilides and 4-pyrrolyl-5-alkyl-1,2,4-triazole(4H)-3-yl thioacetanilides has been described in the article. The key intermediates – 4-amino-5-alkyl-3-mercapto-1,2,4-triazoles... see more

By alkylation of 3-amino-5-methyl-4-oxo-N-aryl-2-thioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine- 6-carboxamides with substituted benzylchlorides and chloroacetic acid the series of novel derivatives of 3-amino-5-methyl-2-(alkylthio)-4-oxo-N-aryl-3,4-dih... see more

The effective method for the synthesis of ethyl 3-alkyl-5-methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxylate derivatives by interaction of diethyl 3-methyl-5-{[(methylsulfanyl)carbothioyl]amino}thiophene-2,4-dicarboxylate with l... see more

This article contains the results antimicrobial and antifungal activity 3-(alkylthio)-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-4-amines (1-6), N-R-eden-3-(nonylthio)-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-4-amines (7-9) and 2-((4-amino-5-(thiophene-... see more

To study the JNK-kinase activity of quinazoline derivatives a series of 4-O-aryl- and 4-N-alkylquinazolines have been synthesized in standard condition of nucleophilic substitution of 4-chloroquinazolines in the presence of potassium carbonate. 4-Chloroqu... see more

In spite of achievements in the sphere of highly effective drugs creation for treating cardiovascular diseases the problem is still urgent since mortality is high because of these diseases, and it takes the 2-nd – 3-d place among the population of industr... see more

1 of 219.599 pages  |  10  records  |  more records»