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1.864.638  Articles
1 of 186.465 pages  |  10  records  |  more records»
Introduction. Plasma markers are widely used along with trepanobiopsy to diagnose the histological stages of chronic diffuse liver diseases.The aim of the study – to determine the activity of cysteine cathepsins B, L, H and the content of proteolysis inhi... see more

The substrate specifity of cathepsin H in untransformed tissues of mammary gland and in tissues of moderately differentiated form of lobular infiltrating breast cancer has been investigated. Cathepsin H from untransformed tissues of mammary glan... see more

The association of lysosomal dysfunction and neurodegeneration has been documented in several neurodegenerative diseases, including Alzheimer’s Disease (AD). Herein, we investigate the association of lysosomal enzymes with AD at different stages of progre... see more

Mitochondria are organelles that are most sensitive to the action of stressors on any cell of the entire organism and exposure to chemicals which can cause its dysfunction and cell death in general. Especially sensitive to adverse conditions are liver mit... see more

Background and objectives: Toxoplasma gondii (T. gondii) is a ubiquitous apicomplexan parasite. As an obligate intracellular parasite, T. gondii must invade host cells to survive and replicate. Five cathepsin proteases are encoded in the genome of T. gond... see more

Background and objectives: Toxoplasma gondii (T. gondii) is a ubiquitous apicomplexan parasite. As an obligate intracellular parasite, T. gondii must invade host cells to survive and replicate. Five cathepsin proteases are encoded in the genome of T. gond... see more

BACKGROUND: There is a prevalence increase of overweight and obesity in Indonesia. Central obesity can lead a variety of chronic diseases through the inflammatory process. There are some markers for low-grade chronic inflammatory, such as cathepsin S, hig... see more

Left ventricular remodeling after myocardial infarction (MI) includes extensive cardiac cell death, inflammatory cell infiltration, cell differentiation, and scar formation. Lysosomal proteases cathepsins participate in all these events during post-MI car... see more

Background. Ovarian cancer has the highest mortality rate of gynaecological cancers. This is partly due to the lack of effective screening markers. Indices of oxidative stress are well-recognized prognostic criteria for tumorous transformation of tissue, ... see more

1 of 186.465 pages  |  10  records  |  more records»