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130  Articles
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Multifaceted relations link ribosome biogenesis to cancer. Ribosome biogenesis takes place in the nucleolus. Clarifying the mechanisms involved in this nucleolar function and its relationship with cell proliferation: (1) allowed the understanding of the r... see more

Ribosomal RNA (rRNA) is extensively edited through base methylation and acetylation, 2′-O-ribose methylation and uridine isomerization. In human rRNA, 95 uridines are predicted to by modified to pseudouridine by ribonucleoprotein complexes sharing f... see more

Background: Treacher Collins Syndrome (TCS) is a craniofacial disorder that has a dominant autosomal disorder in facial development, found 1 in every 50.000 births. The most often manifestations could be mandibulofacial disorder, microtia, atresia of the ... see more

In 2012 were accomplished 100 years from birth of George Emil Palade. He was born in Ia?i, Romania, in November 19, 1912, and after high school, in 1929 he was admitted in “Carol Davila†Medicine Faculty from Bucharest. During university years, he was ... see more

DEAH/RHA helicases are members of a large group of proteins collectively termed DExH-box, which also include Ski2-like and NS3/NPH-II helicases. By binding and remodeling DNA and RNA, DEAH/RHA helicases play critical roles in many cellular processes rangi... see more

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Background : Epigallocatechin-3-gallate (EGCG) is the major polyphenol in green tea and has been considered a natural agent that can help to reduce the risk of obesity.Objective : The aim of this study was to investigate the effects of EGCG on thermogenes... see more

The skeletal muscle occupies about 40% of body mass, one of the largest organs in the body, and it has great plasticity in response to physiological stressors and then alters the contractile and metabolic properties of the muscles. Therefore, healthy stat... see more

The purpose of this study was to investigate the effects of high intensity interval training (HIIT) on PGC-1a and mtDNA of subcutaneous adipose tissue and insulin resistance in obese male rats. After inducing obesity with high fat diet(for 10 weeks), eigh... see more

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