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26.744  Articles
Erythrocytes and neutrophilic leukocytes of human blood have been used as biosensors for in vitro screening of new biologically active functionally substituted oxazoles and nitrogen-containing bisphosphonates with the known fungistatic activity. It has be... see more

A number of acylated derivatives of industrial gallotannin and ellagitannin from alder cones with different substitution degrees of phenolic hydroxyls has been synthesized. The synthesis involved the preparation of a mixture of derivatives with different ... see more

Flexible molecular docking studies for 5,7-dimethyl-6-phenylazo-3H-thiazolo[4,5-b]pyridin-2-ones have been performed with the purpose to reveal their potency as enzymes involved in the arachidonic acid (AA) cascade inhibitors: both cyclooxygenase isoforms... see more

This article represents the research of the interaction of 1-phenyl-5-chloro-1H-pyrazole-4-carboxamide and 1-phenyl-N-formyl-5-chloro-1H-pyrazole-4-carboxamide with hydrazine hydrate in order to get pyrazole derivatives as potential bioactive substances. ... see more

Based on the regularities of the “structure – analgesic activity” relationship revealed earlier in the complex study of the biological properties of numerous N-substituted amides of 1-R-4-hydroxy-6,7-dimethoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acids... see more

Arylmethyliden derivatives of 2,2-dimethyl-1,3-dioxane-4,6-dione; Meldrum`s acid; 6,7-dihydro-7-aryltetrazolo [1,5-a]pyrimidin-5(4H)-ones; synthesis; pharmacological activityCyclocondensations of 1H-tetrazol-5-amine with methylcinnamates, arylmethyliden m... see more

Synthesis of the series of new 4-(1H-pyrrol-1-yl)-5-cyclohexyl-1,2,4-triazole(4H)-3-yl thioacetanilides from 4-amino-5-cyclohexyl-1,2,4-triazole(4H)-3-yl thioacetanilides previously synthesized is described. The target products 3a-z have been obtained by ... see more

Calix[4]arene are known to be a promising scaffold for designing inhibitors of protein tyrosine phosphatases.In this work calix[4]arene mono- and bis-a-hydroxymethylphosphonic acids have been tested in vitro for the inhibitory activity against some therap... see more

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