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21  Articles
1 of 3 pages  |  10  records  |  more records»
La dystrophine (Dp) est le produit du gène de la dystrophie musculaire de Duchenne (DMD). Nous nous sommes intéressés dans ce travail, à l’étude de l’expression et de la distribution des Dps, Ups, et les DAPs membranaires (ß-DG, d- et e-sarcoglycane (SG))... see more

Recent data on Duchenne muscular dystrophy (DMD) show myocyte progenitor’s involvement in the disease pathology often leading to the DMD patient’s death. The molecular mechanism underlying stem cell impairment in DMD has not been described. We... see more

Muscular dystrophy is a group of diseases that result in progressive muscle weakness and atrophy. Duchenne Muscular Dystrophy (DMD) is classified as dystrophinopathy and is an X-linked recessive disease. It is caused by alterations in the dystrophin gene ... see more

The neuromuscular disorder Duchenne muscular dystrophy is a multi-systemic disease that is caused by a primary abnormality in the X-chromosomal Dmd gene. Although progressive skeletal muscle wasting and cardio-respiratory complications are the most seriou... see more

Since all organs (i.e. skeletal, cardiac, smooth muscles and sciatic nerve) are never only taken from a single patient, all these tissues were obtained from one cynomolgus monkey, a model closely resembling humans. This work describes an up-to-date reinve... see more

Duchenne’s muscular dystrophy is an X-linked neuromuscular disease that manifests as muscle atrophy and cardiomyopathy in young boys. However, a considerable percentage of carrier females are often diagnosed with cardiomyopathy at an advanced stage.... see more

Duchenne muscular dystrophy (DMD) is the most common and one of the most serious childhood diseases. It is an X – linked recessive neuromuscular disease, caused by mutations in the dystrophin gene, primarily resulting in skeletal and heart muscle abnormal... see more

Duchenne muscular dystrophy (DMD) is a rare genetic, progressiveand devastating skeletal and cardiac muscle disorder due to mutationof the dystrophin gene that affects 1 in 3500 young males. Currently,there is no curative management for this pathology. Th... see more


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