SUMMARY
The results of this study intend to examine the effect of Current Ratio, Cash Turnover, Total assets Turnover and Debt to Equity Ratio on Profitability in Manufacturing Companies Listed on the Indonesia Stock Exchange 2017-2019 Period. In this study, researchers used Return On Assets (ROA) to calculate the results of Profitability. This study uses a population of manufacturing companies. The use of Purposive Sampling was carried out to determine the sample data from this study with a total sample of 58 companies. This research applies multiple regression data analysis method. The development of research proves that the Profitability variable can be explained by the variables Current Ratio, Cash Turnover, Total Assets Turnover and Debt to Equity Ratio of 38%. The result of this research shows that the Current Ratio partially has no positive and insignificant impact on Profitability (Return On Assets). Partial Cash Turnover has a negative and insignificant impact on Profitability (Return On Assets). Total Assets Turnover partially has a positive and significant impact on Profitability (Return On assets). Debt to Equity Ratio partially does not have a negative and significant impact on Profitability (Return On Assets). Meanwhile, the simultaneous CR, CTR, TATO and DER tests have a positive and significant impact on Profitability (Return On Assets).